Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report
- PMID: 3089198
- DOI: 10.1007/BF01314156
Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report
Abstract
Nineteen influenza virus strains were examined for susceptibility to amantadine-HCl (AMT) and for pH-thresholds of haemagglutinin-induced haemolysis. Whereas pH-thresholds below 5.5 were not seen in AMT-resistant strains, AMT-sensitive strains showed pH-thresholds either below or above 5.5.
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