Brown Adipose Tissue-A Therapeutic Target in Obesity?

doi:10.3389/fphys.2018.01672

. 2018 Nov 23:9:1672.

doi: 10.3389/fphys.2018.01672. eCollection 2018.

Brown Adipose Tissue-A Therapeutic Target in Obesity?

Paul Trayhurn^{1

2}

Affiliations

¹ Clore Laboratory, University of Buckingham, Buckingham, United Kingdom.
² Obesity Biology Unit, University of Liverpool, Liverpool, United Kingdom.

PMID: 30532712
PMCID: PMC6265308
DOI: 10.3389/fphys.2018.01672

Brown Adipose Tissue-A Therapeutic Target in Obesity?

Paul Trayhurn. Front Physiol. 2018.

. 2018 Nov 23:9:1672.

doi: 10.3389/fphys.2018.01672. eCollection 2018.

Author

Paul Trayhurn^{1

2}

Affiliations

¹ Clore Laboratory, University of Buckingham, Buckingham, United Kingdom.
² Obesity Biology Unit, University of Liverpool, Liverpool, United Kingdom.

PMID: 30532712
PMCID: PMC6265308
DOI: 10.3389/fphys.2018.01672

No abstract available

Keywords: beige adipocyte; brown adipocyte; obesity; thermogenesis; uncoupling protein-1.

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References

1. Afzelius B. A. (1970). Brown adipose tissue: its gross anatomy, histology, and cytology in Brown Adipose Tissue, ed. Lindberg O. (New York, NY: American Elsevier; ), 1–31.
1. Arch J. R. (2002). β3-Adrenoceptor agonists: potential, pitfalls and progress. Eur. J. Pharmacol. 440, 99–107. 10.1016/S0014-2999(02)01421-8 - DOI - PubMed
1. Bartelt A., Bruns O. T., Reimer R., Hohenberg H., Ittrich H., Peldschus K., et al. . (2011). Brown adipose tissue activity controls triglyceride clearance. Nat. Med. 17, 200–205. 10.1038/nm.2297 - DOI - PubMed
1. Bartelt A., Heeren J. (2014). Adipose tissue browning and metabolic health. Nat. Rev. Endocrinol. 10, 24–36. 10.1038/nrendo.2013.204 - DOI - PubMed
1. Bouillaud F., Villarroya F., Hentz E., Raimbault S., Cassard A. M., Ricquier D. (1988). Detection of brown adipose tissue uncoupling protein mRNA in adult humans by a genomic probe. Clin. Sci. 75, 21–27. 10.1042/cs0750021 - DOI - PubMed

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[1] Afzelius B. A. (1970). Brown adipose tissue: its gross anatomy, histology, and cytology in Brown Adipose Tissue, ed. Lindberg O. (New York, NY: American Elsevier; ), 1–31.

[2] Afzelius B. A. (1970). Brown adipose tissue: its gross anatomy, histology, and cytology in Brown Adipose Tissue, ed. Lindberg O. (New York, NY: American Elsevier; ), 1–31.

[3] Arch J. R. (2002). β3-Adrenoceptor agonists: potential, pitfalls and progress. Eur. J. Pharmacol. 440, 99–107. 10.1016/S0014-2999(02)01421-8 - DOI - PubMed

[4] Arch J. R. (2002). β3-Adrenoceptor agonists: potential, pitfalls and progress. Eur. J. Pharmacol. 440, 99–107. 10.1016/S0014-2999(02)01421-8 - DOI - PubMed

[5] Bartelt A., Bruns O. T., Reimer R., Hohenberg H., Ittrich H., Peldschus K., et al. . (2011). Brown adipose tissue activity controls triglyceride clearance. Nat. Med. 17, 200–205. 10.1038/nm.2297 - DOI - PubMed

[6] Bartelt A., Bruns O. T., Reimer R., Hohenberg H., Ittrich H., Peldschus K., et al. . (2011). Brown adipose tissue activity controls triglyceride clearance. Nat. Med. 17, 200–205. 10.1038/nm.2297 - DOI - PubMed

[7] Bartelt A., Heeren J. (2014). Adipose tissue browning and metabolic health. Nat. Rev. Endocrinol. 10, 24–36. 10.1038/nrendo.2013.204 - DOI - PubMed

[8] Bartelt A., Heeren J. (2014). Adipose tissue browning and metabolic health. Nat. Rev. Endocrinol. 10, 24–36. 10.1038/nrendo.2013.204 - DOI - PubMed

[9] Bouillaud F., Villarroya F., Hentz E., Raimbault S., Cassard A. M., Ricquier D. (1988). Detection of brown adipose tissue uncoupling protein mRNA in adult humans by a genomic probe. Clin. Sci. 75, 21–27. 10.1042/cs0750021 - DOI - PubMed

[10] Bouillaud F., Villarroya F., Hentz E., Raimbault S., Cassard A. M., Ricquier D. (1988). Detection of brown adipose tissue uncoupling protein mRNA in adult humans by a genomic probe. Clin. Sci. 75, 21–27. 10.1042/cs0750021 - DOI - PubMed

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Brown Adipose Tissue-A Therapeutic Target in Obesity?

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Brown Adipose Tissue-A Therapeutic Target in Obesity?

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