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Review
. 2021 Jan;27(1):70-79.
doi: 10.1007/s11655-018-2574-5. Epub 2018 Nov 27.

Classical Chinese Herbal Formulas in the Treatment of Coronary Heart Disease: A Narrative Review

Xin-Hui Lu  1 , Jun Li  2
Affiliations
Review

Classical Chinese Herbal Formulas in the Treatment of Coronary Heart Disease: A Narrative Review

Xin-Hui Lu et al. Chin J Integr Med. 2021 Jan.

Abstract

Objective: To summarize the current evidence for 8 frequently prescribed Chinese herbal formulas (CHF) as treatments for angina pectoris in patients with coronary heart disease (CHD) and the associated adverse reactions.

Methods: Seven electronic databases were screened from their inception through July 2018 for all evidence related to classical CHF for the treatment of patients with CHD.

Results: CHF improves CHD outcomes in terms of angina pectoris, electrocardiogram results, Chinese medicine syndromes and biomarkers iomarkers. The combination of CHF and Western medicine (WM) is more effective on CHD than WM alone. The use of CHF to treat CHD shows the same or better clinical effects as the use of WM alone. The 8 investigated CHF do not induce hepatic and renal toxicity or other serious adverse effects.

Conclusions: The safety and efficacy of 8 frequently prescribed herbal formulas for treating CHD have been confirmed in many studies. The findings of these studies are positive but should be interpreted cautiously due to the poor methodological quality of the randomized controlled trials (RCTs) and meta-analyses. Additional high-quality, multi-center, large-sample RCTs should be performed to confirm these results.

Keywords: Chinese herbal formulas; complementary and alternative medicine; coronary heart disease; review.

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References

    1. Mendis S, Puska P, Norrving B. Global atlas on cardiovascular disease prevention and control. Geneva: World Health Organization; 2011.
    1. Zhu KF, Wang YM, Zhu JZ, et al. National prevalence of coronary heart disease and its relationship with human development index: a systematic review. Eur J Prev Cardiol 2016;23:530–543. - PubMed - DOI
    1. American College of Emergency Physicians, Society for Cardiovascular Angiography and Interventions, O’Gara PT, Kushner FG, Ascheim DD, Casey DE, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2013;61:485-510.
    1. Hawk C, Ndetan H, Evans MW, Jr. Potential role of complementary and alternative health care providers in chronic disease prevention and health promotion: an analysis of National Health Interview Survey data. Prev Med 2012;54:18–22. - PubMed - DOI
    1. Hao P, Jiang F, Cheng J, et al. Traditional Chinese medicine for cardiovascular disease: evidence and potential mechanisms. J Am Coll Cardiol 2017;69:2952–2966. - PubMed - DOI

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