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Review
. 1986:120:23-38.
doi: 10.1002/9780470513309.ch3.

Organization and expression of the genome of bovine papillomavirus type 1

Review

Organization and expression of the genome of bovine papillomavirus type 1

U Pettersson et al. Ciba Found Symp. 1986.

Abstract

The viral mRNAs present in C127 cells transformed by bovine papillomavirus type 1 (BPV-1) have been mapped by a variety of techniques, including S1 nuclease analysis, Northern blot analysis, primer extension and electron microscopic heteroduplex analysis. The results reveal a very complex mRNA pattern, comprising at least five types of spliced cytoplasmic mRNAs. Both unspliced and partially processed nuclear RNA species have also been identified. The transforming region of BPV-1 contains several promoter regions. A major cap site is located at coordinate 1 and another putative cap site at coordinate 31. A third candidate cap site maps around coordinate 39.

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