Renin-Angiotensin System and Cardiovascular Functions

doi:10.1161/ATVBAHA.118.311282

Review

. 2018 Jul;38(7):e108-e116.

doi: 10.1161/ATVBAHA.118.311282.

Renin-Angiotensin System and Cardiovascular Functions

Chia-Hua Wu^{1

2}, Shayan Mohammadmoradi^{1

2}, Jeff Z Chen^{1

3}, Hisashi Sawada¹, Alan Daugherty^{1

2

3}, Hong S Lu^{4

2

3}

Affiliations

¹ From the Saha Cardiovascular Research Center (C.-H.W., S.M., J.Z.C., H.S., A.D., H.S.L.).
² Department of Pharmacology and Nutritional Sciences (C.-H.W., S.M., A.D., H.S.L.).
³ Department of Physiology (J.Z.C., A.D., H.S.L.), University of Kentucky, Lexington.
⁴ From the Saha Cardiovascular Research Center (C.-H.W., S.M., J.Z.C., H.S., A.D., H.S.L.) hong.lu@uky.edu.

PMID: 29950386
PMCID: PMC6039412
DOI: 10.1161/ATVBAHA.118.311282

Review

Renin-Angiotensin System and Cardiovascular Functions

Chia-Hua Wu et al. Arterioscler Thromb Vasc Biol. 2018 Jul.

. 2018 Jul;38(7):e108-e116.

doi: 10.1161/ATVBAHA.118.311282.

Authors

Chia-Hua Wu^{1

2}, Shayan Mohammadmoradi^{1

2}, Jeff Z Chen^{1

3}, Hisashi Sawada¹, Alan Daugherty^{1

2

3}, Hong S Lu^{4

2

3}

Affiliations

¹ From the Saha Cardiovascular Research Center (C.-H.W., S.M., J.Z.C., H.S., A.D., H.S.L.).
² Department of Pharmacology and Nutritional Sciences (C.-H.W., S.M., A.D., H.S.L.).
³ Department of Physiology (J.Z.C., A.D., H.S.L.), University of Kentucky, Lexington.
⁴ From the Saha Cardiovascular Research Center (C.-H.W., S.M., J.Z.C., H.S., A.D., H.S.L.) hong.lu@uky.edu.

PMID: 29950386
PMCID: PMC6039412
DOI: 10.1161/ATVBAHA.118.311282

No abstract available

Keywords: angiotensin; aortic aneurysms; atherosclerosis; cardiovascular disease; rennin–angiotensin system.

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References

1. Wu C, Lu H, Cassis LA, Daugherty A. Molecular and pathophysiological features of angiotensinogen: a mini review. N Am J Med Sci (Boston) 2011;4:183–190. - PMC - PubMed
1. Lu H, Cassis LA, Kooi CW, Daugherty A. Structure and functions of angiotensinogen. Hypertens Res. 2016;39:492–500. doi: 10.1038/hr.2016.17. - PMC - PubMed
1. Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc Natl Acad Sci USA. 1995;92:3521–3525. - PMC - PubMed
1. Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. Am J Physiol. 1997;272(4)(pt 2):F515–F520. doi: 10.1152/ajprenal.1997.272.4.F515. - PubMed
1. Daugherty A, Rateri DL, Lu H, Inagami T, Cassis LA. Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor. Circulation. 2004;110:3849–3857. doi: 10.1161/01.CIR.0000150540.54220.C4. - PubMed

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[1] Wu C, Lu H, Cassis LA, Daugherty A. Molecular and pathophysiological features of angiotensinogen: a mini review. N Am J Med Sci (Boston) 2011;4:183–190. - PMC - PubMed

[2] Wu C, Lu H, Cassis LA, Daugherty A. Molecular and pathophysiological features of angiotensinogen: a mini review. N Am J Med Sci (Boston) 2011;4:183–190. - PMC - PubMed

[3] Lu H, Cassis LA, Kooi CW, Daugherty A. Structure and functions of angiotensinogen. Hypertens Res. 2016;39:492–500. doi: 10.1038/hr.2016.17. - PMC - PubMed

[4] Lu H, Cassis LA, Kooi CW, Daugherty A. Structure and functions of angiotensinogen. Hypertens Res. 2016;39:492–500. doi: 10.1038/hr.2016.17. - PMC - PubMed

[5] Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc Natl Acad Sci USA. 1995;92:3521–3525. - PMC - PubMed

[6] Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc Natl Acad Sci USA. 1995;92:3521–3525. - PMC - PubMed

[7] Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. Am J Physiol. 1997;272(4)(pt 2):F515–F520. doi: 10.1152/ajprenal.1997.272.4.F515. - PubMed

[8] Oliverio MI, Best CF, Kim HS, Arendshorst WJ, Smithies O, Coffman TM. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. Am J Physiol. 1997;272(4)(pt 2):F515–F520. doi: 10.1152/ajprenal.1997.272.4.F515. - PubMed

[9] Daugherty A, Rateri DL, Lu H, Inagami T, Cassis LA. Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor. Circulation. 2004;110:3849–3857. doi: 10.1161/01.CIR.0000150540.54220.C4. - PubMed

[10] Daugherty A, Rateri DL, Lu H, Inagami T, Cassis LA. Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor. Circulation. 2004;110:3849–3857. doi: 10.1161/01.CIR.0000150540.54220.C4. - PubMed

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Renin-Angiotensin System and Cardiovascular Functions

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