Review
doi: 10.1007/BF00713057.
Crossbridge behaviour during muscle contraction
- PMID: 2993356
- DOI: 10.1007/BF00713057
Item in Clipboard
Review
Crossbridge behaviour during muscle contraction
J Muscle Res Cell Motil.
1985 Apr.
Abstract
A number of recent observations by probe and X-ray methods on the behaviour of crossbridges during contraction is considered in relation to the energetics of the process. It is shown that a self-consistent picture of the crossbridge cycle, compatible with these observations and involving strongly and weakly attached crossbridges, can be obtained providing that the tension-generating part of the crossbridge stroke is only about 40 A i.e. about one-third of the usually accepted value. The myosin head subunits in the tension-generating bridges could have a configuration close to that of rigor. A mechanism is suggested whereby rapid tension recovery after quick releases up to 120 A could still be produced by such a system.
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