Review
Immunopathogenesis of HIV infection
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- PMID: 2976089
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Review
Immunopathogenesis of HIV infection
J Acquir Immune Defic Syndr (1988).
1988.
Abstract
HIV may cause CD4-positive T cell depletion not only by direct infection but by causing damage to normal maintenance mechanisms. Findings in support of such a concept are presented. Results suggesting that immune reactions against HIV may contain elements of a negative nature are presented, in particular in relation to viral enhancement by antibodies. A question is also raised whether HIV replication has been proved to be reduced in a significant manner by immune reactions.
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