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Review
. 2018 Apr;8(4):207.
doi: 10.1007/s13205-018-1227-x. Epub 2018 Apr 4.

Therapeutic applications of bacterial pigments: a review of current status and future opportunities

Muhammad Numan  1   2 , Samina Bashir  1 , Roqayya Mumtaz  1 , Sibgha Tayyab  1 , Najeeb Ur Rehman  2 , Abdul Latif Khan  2 , Zabta Khan Shinwari  1   3 , Ahmed Al-Harrasi  2
Affiliations
Review

Therapeutic applications of bacterial pigments: a review of current status and future opportunities

Muhammad Numan et al. 3 Biotech. 2018 Apr.

Abstract

Non-toxicity, biodegradability and non-carcinogenicity of the natural pigments, dyes and colorants make them an attractive source for human use. Bacterial pigments are colored metabolites secreted by bacteria under stress. The industrial uses of bacterial pigments have increased many folds because of several advantages over the synthetic pigments. Among natural resources, bacterial pigments are mostly preferred because of simple culturing and pigment extraction techniques, scaling up and being time economical. Generally, the bacterial pigments are safe for human use and therefore have a wide range of applications in pharmaceutical, textile, cosmetics and food industries. Therapeutic nature of the bacterial pigments is revealed because of their antimicrobial, anticancer, cytotoxic and remarkable antioxidant properties. Owing to the importance of bacterial pigments it was considered important to produce a comprehensive review of literature on the therapeutic and industrial potential of bacterial pigments. Extensive literature has been reviewed on the biomedical application of bacterial pigments while further opportunities and future challenges have been discussed.

Keywords: Antibacterial; Anticancer; Antileishmania; Antioxidant; Bacteria; Natural pigments.

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Conflict of interest statement

Compliance with ethical standardsThe authors declare that there is no conflict of interest regarding the publication of this manuscript.

Figures

Fig. 1
Fig. 1
Extraction of bacterial pigments
Fig. 2
Fig. 2
Applications of bacterial pigments in therapeutics
Fig. 3
Fig. 3
Extraction and applications of bacterial pigments
Fig. 4
Fig. 4
Applications of bacterial pigments
See this image and copyright information in PMC

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References

    1. Aberoumand A. A review article on edible pigments properties and sources as natural biocolorants in foodstuff and food industry. World J Dairy Food Sci. 2011;6(1):71–78.
    1. Ahmad WA, Ahmad WYW, Zakaria ZA, Yusof NZ (2012) Application of bacterial pigments as colorant. In: Application of bacterial pigments as colorant. Springer, pp 57–74
    1. Alihosseini F, Ju KS, Lango J, Hammock BD, Sun G. Antibacterial colorants: characterization of prodiginines and their applications on textile materials. Biotechnol Prog. 2008;24(3):742–747. doi: 10.1021/bp070481r. - DOI - PMC - PubMed
    1. Andrighetti-Fröhner CR, Antonio RV, Creczynski-Pasa TB, Barardi CRM, Simões CMO. Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum. Memórias do Instituto Oswaldo Cruz. 2003;98(6):843–848. doi: 10.1590/S0074-02762003000600023. - DOI - PubMed
    1. Arun N, Singh D. Differential response of Dunaliella salina and Dunaliella tertiolecta isolated from brines of Sambhar Salt Lake of Rajasthan (India) to salinities: a study on growth, pigment and glycerol synthesis. J Mar Biol Assoc India. 2013;55(1):65–70. doi: 10.6024/jmbai.2013.55.1.01758-11. - DOI

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