Coxiella burnetii Lipopolysaccharide: What Do We Know?

doi:10.3390/ijms18122509

Review

. 2017 Nov 23;18(12):2509.

doi: 10.3390/ijms18122509.

Coxiella burnetii Lipopolysaccharide: What Do We Know?

Prasad Abnave¹, Xavier Muracciole², Eric Ghigo³

Affiliations

¹ Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK. prasadabnave@gmail.com.
² Department of Radiotherapy Oncology, CHU de la Timone, Assistance Publique-Hopitaux Marseille, 13385 Marseille, France. xavier.muracciole@gmail.com.
³ Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut Hospitalier Universitaire Méditerranée-Infection, 19-21 Bd Jean Moulin, CEDEX 05, 13385 Marseille, France. eric.ghigo@gmail.com.

PMID: 29168790
PMCID: PMC5751112
DOI: 10.3390/ijms18122509

Review

Coxiella burnetii Lipopolysaccharide: What Do We Know?

Prasad Abnave et al. Int J Mol Sci. 2017.

. 2017 Nov 23;18(12):2509.

doi: 10.3390/ijms18122509.

Authors

Prasad Abnave¹, Xavier Muracciole², Eric Ghigo³

Affiliations

¹ Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK. prasadabnave@gmail.com.
² Department of Radiotherapy Oncology, CHU de la Timone, Assistance Publique-Hopitaux Marseille, 13385 Marseille, France. xavier.muracciole@gmail.com.
³ Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut Hospitalier Universitaire Méditerranée-Infection, 19-21 Bd Jean Moulin, CEDEX 05, 13385 Marseille, France. eric.ghigo@gmail.com.

PMID: 29168790
PMCID: PMC5751112
DOI: 10.3390/ijms18122509

Abstract

A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of C. burnetii is one of the major factors involved in this immune hijacking because of its atypical composition and structure. Thus, the aim of this mini-review is to summarize the repressive effects of C. burnetii LPS on the antibacterial immunity of cells.

Keywords: Coxiella burnetii; Q fever; lipopolysaccharide; phagosome; virenose.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

1. Maurin M., Benoliel A.M., Bongrand P., Raoult D. Phagolysosomal alkalinization and the bactericidal effect of antibiotics: The Coxiella burnetii paradigm. J. Infect. Dis. 1992;166:1097–1102. doi: 10.1093/infdis/166.5.1097. - DOI - PubMed
1. Eldin C., Melenotte C., Mediannikov O., Ghigo E., Million M., Edouard S., Mege J.L., Maurin M., Raoult D. From Q fever to Coxiella burnetii infection: A paradigm change. Clin. Microbiol. Rev. 2017;30:115–190. doi: 10.1128/CMR.00045-16. - DOI - PMC - PubMed
1. Maurin M., Raoult D. Q fever. Clin. Microbiol. Rev. 1999;12:518–553. - PMC - PubMed
1. Houpikian P., Habib G., Mesana T., Raoult D. Changing clinical presentation of Q fever endocarditis. Clin. Infect. Dis. 2002;34:E28–E31. doi: 10.1086/338873. - DOI - PubMed
1. Gimenez D.F. Staining rickettsiae in yolk-sac cultures. Stain Technol. 1964;39:135–140. doi: 10.3109/10520296409061219. - DOI - PubMed

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[1] Maurin M., Benoliel A.M., Bongrand P., Raoult D. Phagolysosomal alkalinization and the bactericidal effect of antibiotics: The Coxiella burnetii paradigm. J. Infect. Dis. 1992;166:1097–1102. doi: 10.1093/infdis/166.5.1097. - DOI - PubMed

[2] Maurin M., Benoliel A.M., Bongrand P., Raoult D. Phagolysosomal alkalinization and the bactericidal effect of antibiotics: The Coxiella burnetii paradigm. J. Infect. Dis. 1992;166:1097–1102. doi: 10.1093/infdis/166.5.1097. - DOI - PubMed

[3] Eldin C., Melenotte C., Mediannikov O., Ghigo E., Million M., Edouard S., Mege J.L., Maurin M., Raoult D. From Q fever to Coxiella burnetii infection: A paradigm change. Clin. Microbiol. Rev. 2017;30:115–190. doi: 10.1128/CMR.00045-16. - DOI - PMC - PubMed

[4] Eldin C., Melenotte C., Mediannikov O., Ghigo E., Million M., Edouard S., Mege J.L., Maurin M., Raoult D. From Q fever to Coxiella burnetii infection: A paradigm change. Clin. Microbiol. Rev. 2017;30:115–190. doi: 10.1128/CMR.00045-16. - DOI - PMC - PubMed

[5] Maurin M., Raoult D. Q fever. Clin. Microbiol. Rev. 1999;12:518–553. - PMC - PubMed

[6] Maurin M., Raoult D. Q fever. Clin. Microbiol. Rev. 1999;12:518–553. - PMC - PubMed

[7] Houpikian P., Habib G., Mesana T., Raoult D. Changing clinical presentation of Q fever endocarditis. Clin. Infect. Dis. 2002;34:E28–E31. doi: 10.1086/338873. - DOI - PubMed

[8] Houpikian P., Habib G., Mesana T., Raoult D. Changing clinical presentation of Q fever endocarditis. Clin. Infect. Dis. 2002;34:E28–E31. doi: 10.1086/338873. - DOI - PubMed

[9] Gimenez D.F. Staining rickettsiae in yolk-sac cultures. Stain Technol. 1964;39:135–140. doi: 10.3109/10520296409061219. - DOI - PubMed

[10] Gimenez D.F. Staining rickettsiae in yolk-sac cultures. Stain Technol. 1964;39:135–140. doi: 10.3109/10520296409061219. - DOI - PubMed

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Coxiella burnetii Lipopolysaccharide: What Do We Know?

Affiliations

Coxiella burnetii Lipopolysaccharide: What Do We Know?

Authors

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Conflict of interest statement

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