Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Nov 20;27(22):R1233-R1236.
doi: 10.1016/j.cub.2017.10.004.

Endosomal Trafficking: Retromer and Retriever Are Relatives in Recycling

Affiliations
Free article
Comment

Endosomal Trafficking: Retromer and Retriever Are Relatives in Recycling

David C Gershlick et al. Curr Biol. .
Free article

Abstract

Transmembrane proteins are sorted from endosomes to avoid lysosomal degradation. A recent study has identified a new multimeric complex called retriever that is essential for recycling numerous cell-surface cargoes from endosomes and is structurally and functionally related to the well-characterised retromer complex.

PubMed Disclaimer

Comment on

  • Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.
    McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ. McNally KE, et al. Nat Cell Biol. 2017 Oct;19(10):1214-1225. doi: 10.1038/ncb3610. Epub 2017 Sep 11. Nat Cell Biol. 2017. PMID: 28892079 Free PMC article.

Similar articles

Cited by

Substances

LinkOut - more resources