Endosomal Trafficking: Retromer and Retriever Are Relatives in Recycling
- PMID: 29161566
- DOI: 10.1016/j.cub.2017.10.004
Endosomal Trafficking: Retromer and Retriever Are Relatives in Recycling
Abstract
Transmembrane proteins are sorted from endosomes to avoid lysosomal degradation. A recent study has identified a new multimeric complex called retriever that is essential for recycling numerous cell-surface cargoes from endosomes and is structurally and functionally related to the well-characterised retromer complex.
Published by Elsevier Ltd.
Comment on
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Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.Nat Cell Biol. 2017 Oct;19(10):1214-1225. doi: 10.1038/ncb3610. Epub 2017 Sep 11. Nat Cell Biol. 2017. PMID: 28892079 Free PMC article.
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