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Comparative Study
. 1989 Feb;57(2):643-4.
doi: 10.1128/iai.57.2.643-644.1989.

Ceruloplasmin can substitute for rabbit serum in stimulating the growth of Treponema denticola

M Suzuki  1 , W J Loesche
Affiliations
Comparative Study

Ceruloplasmin can substitute for rabbit serum in stimulating the growth of Treponema denticola

M Suzuki et al. Infect Immun. 1989 Feb.

Abstract

The growth of Treponema denticola in a complex medium was stimulated by human ceruloplasmin and, to a lesser extent, albumin, alpha-1-antitrypsin, alpha-1-acid glycoprotein, and alpha-2-macroglobulin. Human ceruloplasmin could stimulate growth of T. denticola as well as or better than 5% rabbit serum, with a dose-response relationship of between 1 and 5 mg of ceruloplasmin per ml of culture medium. These results suggest that ceruloplasmin could substitute for rabbit serum in stimulating the growth of T. denticola.

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