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Review
. 1988 Nov;116(5 Pt 2):1426-34.
doi: 10.1016/0002-8703(88)90135-4.

Celiprolol in hypertension

S H Taylor  1
Affiliations
Review

Celiprolol in hypertension

S H Taylor. Am Heart J. 1988 Nov.

Abstract

Celiprolol is a third-generation, beta-adrenoceptor antagonist with ancillary pharmacologic properties that are potentially advantageous in the treatment of hypertension. Celiprolol provides 24-hour control of blood pressure and in formal clinical trials has been found superior to a placebo and of equal efficacy to other commonly used beta-blocking drugs. It has also been found to be equally as effective as enalapril in lowering the resting blood pressure and superior in controlling the increases in blood pressure and heart rate during exercise. Celiprolol is known to exert a beneficial effect on the atheroprotective components of the risk factors for coronary heart disease, such as cholesterol triglyceride, and fibrinogen. Therefore the primary attributes of beta-blockade are uniquely advanced by celiprolol's ancillary pharmacologic activities.

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