A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

doi:10.1016/j.ctim.2017.08.014

Review

. 2017 Oct:34:129-140.

doi: 10.1016/j.ctim.2017.08.014. Epub 2017 Aug 25.

A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

Neda Nayebi¹, Nahid Khalili², Mohammad Kamalinejad³, Majid Emtiazy⁴

Affiliations

¹ Department of Traditional Medicine, Faculty of Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Yazd 8951737915, Iran. Electronic address: ned_nayeb@yahoo.com.
² Department of Endocrinology, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: nkhalili09@gmail.com.
³ Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran. Electronic address: mkamalinejad@yahoo.com.
⁴ Department of Traditional Medicine, Faculty of Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Yazd 8951737915, Iran; The Research Center of The Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: Dr.emtiazy@yahoo.com.

PMID: 28917365
DOI: 10.1016/j.ctim.2017.08.014

Review

A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

Neda Nayebi et al. Complement Ther Med. 2017 Oct.

. 2017 Oct:34:129-140.

doi: 10.1016/j.ctim.2017.08.014. Epub 2017 Aug 25.

Authors

Neda Nayebi¹, Nahid Khalili², Mohammad Kamalinejad³, Majid Emtiazy⁴

Affiliations

¹ Department of Traditional Medicine, Faculty of Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Yazd 8951737915, Iran. Electronic address: ned_nayeb@yahoo.com.
² Department of Endocrinology, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: nkhalili09@gmail.com.
³ Department of Pharmacognosy, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran 1985717443, Iran. Electronic address: mkamalinejad@yahoo.com.
⁴ Department of Traditional Medicine, Faculty of Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Ardakan, Yazd 8951737915, Iran; The Research Center of The Iranian Traditional Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: Dr.emtiazy@yahoo.com.

PMID: 28917365
DOI: 10.1016/j.ctim.2017.08.014

Abstract

Rosa damascena Mill. is one of the most famous ornamental plants cultivated all over the world mostly for perfumery industries. Traditionally it has been used as an astringent, analgesic, cardiac and intestinal tonic.The paucity ofauthoritative monographs urged usto summarize its clinical effectiveness and safety with acomprehensive review of the literature. "PUBMED", "SCOPUS", "WEBOF SCIENCE" were searched up to April 30, 2017 with search terms:("Rosa damascena" OR "Damask Rose"). All human studies with any mono-preparation were included. In vitro and animal studies from "PUBMED"were also reviewed and outlined. Of "1000" identified publications, twelveeligibleclinical trials were retrieved. Antimicrobial, anti-inflammatory, antioxidant, anticancer, protective neuronal, cardiac, gastrointestinal and hepatic effectsin 30 in vitro and 21 animal studies were also shown. there are promising evidences for the effectiveness and safety of Rosa damascena Mill in pain relief, but confirmatory studies withstandardized products is suggested.

Keywords: Clinical efficacy; Damask rose; Herb; Herbal medicine; Rosa damascena; Systematic review.

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A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

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A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties

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