Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Aug 24:59:e59.
doi: 10.1590/S1678-9946201759059.

An unusual case of bacillary angiomatosis in the oral cavity of an AIDS patient who had no concomitant tegumentary lesions - case report and review

Walter de Araujo Eyer-Silva  1 , Pedro Eugênio Mendes Arena Soares  1 , Marcelo Costa Velho Mendes de Azevedo  1 , Guilherme Almeida Rosa da Silva  1 , Dario José Hart Pontes Signorini  1 , Rogerio Neves-Motta  1 , Jorge Francisco da Cunha Pinto  1 , Lívia Machado Moura  1 , Rodrigo Panno Basílio-de-Oliveira  1 , Luciana Ferreira de Araujo  1 , Alexsandra Rodrigues de Mendonça Favacho  2 , Elba Regina Sampaio Lemos  2
Affiliations
Case Reports

An unusual case of bacillary angiomatosis in the oral cavity of an AIDS patient who had no concomitant tegumentary lesions - case report and review

Walter de Araujo Eyer-Silva et al. Rev Inst Med Trop Sao Paulo. .

Abstract

Bacillary angiomatosis (BA) is an angioproliferative disease of immunocompromised patients that usually presents as vascular tumors in the skin and subcutaneous tissues. It is caused by chronic infections with either Bartonella henselae or B. quintana. Oral cavity BA is exceedingly rare and even rarer without simultaneous cutaneous disease. We report herein the case of a 51-year-old HIV-infected man who presented severe odynophagia and an eroded lesion on the hard palate that progressed to an oronasal fistula. No cutaneous lesions were recorded. Doxycycline led to complete resolution. To the best of our knowledge, only six previous cases of oral BA without tegumentary disease have been previously reported and none of them progressed to fistula.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTERESTS

The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1. - Clinical image of a 51-year-old HIV-infected male patient who presented with a several week history of dysphagia and odynophagia. A painful bluish-purple papular lesion with an erosive center-on the right palatoglossal arch is seen. The lesion was very painful
Figure 2
Figure 2. - A) Low power (original magnification 10x) hematoxylin and eosin stain shows neutrophilic inflammation and capillary proliferation; B) lobular vascular proliferation with epithelioid endothelial cells and an intervening edematous stroma with an inflammatory infiltrate of multiple neutrophils (original magnification 20x); C) Clumps of small extracellular, argyrophilic bacilli as unveiled by Warthin-Starry silver stain (original magnification 40x)
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Angelakis E, Raoult D. Pathogenicity and treatment of Bartonella infections. Int J Antimicrob Agents. 2014;44:16–25. - PubMed
    1. Stoler MH, Bonfiglio TA, Steigbigel RT, Pereira M. An atypical subcutaneous infection associated with acquired immune deficiency syndrome. Am J Clin Pathol. 1983;80:714–718. - PubMed
    1. Cockerell CJ, Whitlow MA, Webster GF, Friedman-Kien AE. Epithelioid angiomatosis: a distinct vascular disorder in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Lancet. 1987;2:654–656. - PubMed
    1. Axiotis CA, Schwartz R, Jennings TA, Glaser N. AIDS-related angiomatosis. Am J Dermatopathol. 1989;11:177–181. - PubMed
    1. van der Wouw PA, Hadderingh RJ, Reiss P, Hulsebosch HJ, Walford N, Lange JM. Disseminated cat-scratch disease in a patient with AIDS. AIDS. 1989;3:751–753. - PubMed

Publication types

MeSH terms