Review
doi: 10.1016/j.coph.2017.07.005.
Epub 2017 Aug 10.
Targeting gastrointestinal nutrient sensing mechanisms to treat obesity
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- PMID: 28802874
- DOI: 10.1016/j.coph.2017.07.005
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Review
Targeting gastrointestinal nutrient sensing mechanisms to treat obesity
Curr Opin Pharmacol.
2017 Dec.
Free article
Abstract
Gut hormones have important roles in the regulation of appetite and glucose homeostasis. Understanding how macronutrient sensing in the gastrointestinal tract modulates gut hormone release may reveal novel pharmacological or dietary approaches to metabolic disease. In this short review we discuss the mechanisms by which the gut senses macronutrients and the products of macronutrient digestion, and their putative utility in treating obesity and related conditions.
Copyright © 2017 Elsevier Ltd. All rights reserved.
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