The c-erb-A protein is a high-affinity receptor for thyroid hormone
- PMID: 2879242
- DOI: 10.1038/324635a0
The c-erb-A protein is a high-affinity receptor for thyroid hormone
Abstract
Hormone binding and localization of the c-erb-A protein suggest that it is a receptor for thyroid hormone, a nuclear protein that binds to DNA and activates transcription. In contrast, the product of the viral oncogene v-erb-A is defective in binding the hormone but is still located in the nucleus.
Similar articles
-
The c-erb-A gene encodes a thyroid hormone receptor.Nature. 1986 Dec 18-31;324(6098):641-6. doi: 10.1038/324641a0. Nature. 1986. PMID: 2879243
-
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone.Nature. 1987 Oct 22-28;329(6141):738-41. doi: 10.1038/329738a0. Nature. 1987. PMID: 3313046
-
Mapping of functional domains within the v-erb A oncogene protein: the remnants of the hormone binding domain play multiple, vital roles in protein action.Oncogene. 1990 Sep;5(9):1303-11. Oncogene. 1990. PMID: 2170895
-
Thyroid hormone and neoplastic transformation.Crit Rev Oncog. 1990;1(4):389-408. Crit Rev Oncog. 1990. PMID: 1982076 Review. No abstract available.
-
Ets oncogene family.Indian J Exp Biol. 1997 Apr;35(4):315-22. Indian J Exp Biol. 1997. PMID: 9315229 Review.
Cited by
-
Identification of a Thyroid Hormone Binding Site in Hsp90 with Implications for Its Interaction with Thyroid Hormone Receptor Beta.ACS Omega. 2022 Aug 9;7(33):28932-28945. doi: 10.1021/acsomega.2c02331. eCollection 2022 Aug 23. ACS Omega. 2022. PMID: 36033668 Free PMC article.
-
c-erbA encodes multiple proteins in chicken erythroid cells.Mol Cell Biol. 1988 Oct;8(10):4155-61. doi: 10.1128/mcb.8.10.4155-4161.1988. Mol Cell Biol. 1988. PMID: 3054510 Free PMC article.
-
µ-Crystallin: A thyroid hormone binding protein.Endocr Regul. 2021 May 21;55(2):89-102. doi: 10.2478/enr-2021-0011. Endocr Regul. 2021. PMID: 34020530 Free PMC article. Review.
-
Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.Mol Cell Biol. 1987 May;7(5):2019-23. doi: 10.1128/mcb.7.5.2019-2023.1987. Mol Cell Biol. 1987. PMID: 3299059 Free PMC article.
-
Thyroid hormone induces constitutive keratin gene expression during Xenopus laevis development.Mol Cell Biol. 1989 May;9(5):1823-31. doi: 10.1128/mcb.9.5.1823-1831.1989. Mol Cell Biol. 1989. PMID: 2473388 Free PMC article.
Publication types
MeSH terms
Substances
Associated data
- Actions
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Molecular Biology Databases