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. 2015 Oct;1(2):90-95.
doi: 10.15420/cfr.2015.1.2.90.

Fluid Management in Patients with Chronic Heart Failure

Pierpaolo Pellicori  1 , Kuldeep Kaur  1 , Andrew L Clark  1
Affiliations

Fluid Management in Patients with Chronic Heart Failure

Pierpaolo Pellicori et al. Card Fail Rev. 2015 Oct.

Abstract

Congestion, or fluid overload, is a classic clinical feature of patients presenting with heart failure patients, and its presence is associated with adverse outcome. However, congestion is not always clinically evident, and more objective measures of congestion than simple clinical examination may be helpful. Although diuretics are the mainstay of treatment for congestion, no randomised trials have shown the effects of diuretics on mortality in chronic heart failure patients. Furthermore, appropriate titration of diuretics in this population is unclear. Research is required to determine whether a robust method of detecting - and then treating - subclinical congestion improves outcomes.

Keywords: Diuretics; chronic heart failure; congestion; review; treatment.

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Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. A Simplified Pathophysiology of Pulmonary Oedema or Peripheral Oedema Development in Patients with HFREF or HeFNEF
See this image and copyright information in PMC

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References

    1. Cleland JG, McDonagh T, Rigby AS, et al; National Heart Failure Audit Team for England and Wales. The national heart failure audit for England and Wales 2008–2009. Heart. 2011;97:876–886. - PubMed
    1. Carson PE, Anand IS, Win S, et al. The Hospitalization Burden and Post-Hospitalization Mortality Risk in Heart Failure With Preserved Ejection Fraction: Results From the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction). JACC Heart Fail. 2015;3:429–441. - PubMed
    1. Clark AL, Cleland JG. Causes and treatment of oedema in patients with heart failure. Nat Rev Cardiol. 2013;10:156–170. - PubMed
    1. Shoaib A, Waleed M, Khan S, et al. Breathlessness at rest is not the dominant presentation of patients admitted with heart failure. Eur J Heart Fail. 2014;16:1283–1291. - PubMed
    1. Ambrosy AP, Pang PS, Khan S, et al; EVEREST Trial Investigators. Clinical course and predictive value of congestion during hospitalisation in patients admitted for worsening signs and symptoms of heart failure with reduced ejection fraction: findings from the EVEREST trial. Eur Heart J. 2013;34:835–843. - PubMed