Human acute leukemia induced pluripotent stem cells: a unique model for investigating disease development and pathogenesis

doi:10.21037/sci.2017.05.12

Editorial

. 2017 Jun 13:4:55.

doi: 10.21037/sci.2017.05.12. eCollection 2017.

Human acute leukemia induced pluripotent stem cells: a unique model for investigating disease development and pathogenesis

Clara Bueno^{1

2}, Pablo Menendez^{1

2

3}

Affiliations

¹ Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.
² Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.
³ Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

PMID: 28725651
PMCID: PMC5503908
DOI: 10.21037/sci.2017.05.12

Editorial

Human acute leukemia induced pluripotent stem cells: a unique model for investigating disease development and pathogenesis

Clara Bueno et al. Stem Cell Investig. 2017.

. 2017 Jun 13:4:55.

doi: 10.21037/sci.2017.05.12. eCollection 2017.

Authors

Clara Bueno^{1

2}, Pablo Menendez^{1

2

3}

Affiliations

¹ Josep Carreras Leukemia Research Institute and Department of Biomedicine, School of Medicine, University of Barcelona, Barcelona, Spain.
² Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), ISCIII, Barcelona, Spain.
³ Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

PMID: 28725651
PMCID: PMC5503908
DOI: 10.21037/sci.2017.05.12

No abstract available

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Conflict of interest statement

Conflicts of Interest: P Menendez is an investigator of the Spanish Cell Therapy cooperative network (TERCEL). C Bueno has no conflicts of interest to declare.

Comment on

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, Wernig M, Wu JC, Majeti R. Chao MP, et al. Cell Stem Cell. 2017 Mar 2;20(3):329-344.e7. doi: 10.1016/j.stem.2016.11.018. Epub 2017 Jan 12. Cell Stem Cell. 2017. PMID: 28089908 Free PMC article.

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References

1. Bueno C, Montes R, Catalina P, et al. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement. Leukemia 2011;25:400-10. 10.1038/leu.2010.284 - DOI - PubMed
1. Sanjuan-Pla A, Bueno C, Prieto C. Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia. Blood 2015;126:2676-85. 10.1182/blood-2015-09-667378 - DOI - PMC - PubMed
1. Thomas D, Majeti R. Biology and relevance of human acute myeloid leukemia stem cells. Blood 2017;129:1577-85. 10.1182/blood-2016-10-696054 - DOI - PMC - PubMed
1. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblasts cultures by defined factors. Cell 2006;126:663-76. 10.1016/j.cell.2006.07.024 - DOI - PubMed
1. Menendez P, Bueno C, Wang L. Human embryonic stem cells: A journey beyond cell replacement therapies. Cytotherapy 2006;8:530-41. 10.1080/14653240601026654 - DOI - PubMed

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[1] Bueno C, Montes R, Catalina P, et al. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement. Leukemia 2011;25:400-10. 10.1038/leu.2010.284 - DOI - PubMed

[2] Bueno C, Montes R, Catalina P, et al. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement. Leukemia 2011;25:400-10. 10.1038/leu.2010.284 - DOI - PubMed

[3] Sanjuan-Pla A, Bueno C, Prieto C. Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia. Blood 2015;126:2676-85. 10.1182/blood-2015-09-667378 - DOI - PMC - PubMed

[4] Sanjuan-Pla A, Bueno C, Prieto C. Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia. Blood 2015;126:2676-85. 10.1182/blood-2015-09-667378 - DOI - PMC - PubMed

[5] Thomas D, Majeti R. Biology and relevance of human acute myeloid leukemia stem cells. Blood 2017;129:1577-85. 10.1182/blood-2016-10-696054 - DOI - PMC - PubMed

[6] Thomas D, Majeti R. Biology and relevance of human acute myeloid leukemia stem cells. Blood 2017;129:1577-85. 10.1182/blood-2016-10-696054 - DOI - PMC - PubMed

[7] Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblasts cultures by defined factors. Cell 2006;126:663-76. 10.1016/j.cell.2006.07.024 - DOI - PubMed

[8] Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblasts cultures by defined factors. Cell 2006;126:663-76. 10.1016/j.cell.2006.07.024 - DOI - PubMed

[9] Menendez P, Bueno C, Wang L. Human embryonic stem cells: A journey beyond cell replacement therapies. Cytotherapy 2006;8:530-41. 10.1080/14653240601026654 - DOI - PubMed

[10] Menendez P, Bueno C, Wang L. Human embryonic stem cells: A journey beyond cell replacement therapies. Cytotherapy 2006;8:530-41. 10.1080/14653240601026654 - DOI - PubMed

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Human acute leukemia induced pluripotent stem cells: a unique model for investigating disease development and pathogenesis

Affiliations

Human acute leukemia induced pluripotent stem cells: a unique model for investigating disease development and pathogenesis

Authors

Affiliations

Conflict of interest statement

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