NK cells suppress the generation of Lyt-2+ cytolytic T cells by suppressing or eliminating dendritic cells
- PMID: 2871105
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NK cells suppress the generation of Lyt-2+ cytolytic T cells by suppressing or eliminating dendritic cells
J Immunol.
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Abstract
Cells highly enriched for natural killer activity suppress the generation of Lyt-2+ cytolytic T cells in one-way mixed lymphocyte cultures. Suppression occurs because natural killer cells suppress or eliminate dendritic cells, which are required for proliferation of both Ly-1+ and Lyt-2+ lymphocytes.
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