Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017:2017:7125057.
doi: 10.1155/2017/7125057. Epub 2017 Apr 20.

Understanding the Mechanisms of Recovery and/or Compensation following Injury

Michael J Hylin  1 , Abigail L Kerr  2 , Ryan Holden  1
Affiliations
Review

Understanding the Mechanisms of Recovery and/or Compensation following Injury

Michael J Hylin et al. Neural Plast. 2017.

Abstract

Injury due to stroke and traumatic brain injury result in significant long-term effects upon behavioral functioning. One central question to rehabilitation research is whether the nature of behavioral improvement observed is due to recovery or the development of compensatory mechanisms. The nature of functional improvement can be viewed from the perspective of behavioral changes or changes in neuroanatomical plasticity that follows. Research suggests that these changes correspond to each other in a bidirectional manner. Mechanisms surrounding phenomena like neural plasticity may offer an opportunity to explain how variables such as experience can impact improvement and influence the definition of recovery. What is more, the intensity of the rehabilitative experiences may influence the ability to recover function and support functional improvement of behavior. All of this impacts how researchers, clinicians, and medical professionals utilize rehabilitation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Jennett B., Bond M. Assessment of outcome after severe brain damage. Lancet. 1975;1(7905):480–484. - PubMed
    1. McMillan T., Wilson L., Ponsford J., Levin H., Teasdale G., Bond M. The Glasgow Outcome Scale-40 years of application and refinement. Nature Reviews Neurology. 2016;12(8):477–485. doi: 10.1038/nrneurol.2016.89. - DOI - PubMed
    1. Nakase-Richardson R., Whyte J., Giacino J. T., et al. Longitudinal outcome of patients with disordered consciousness in the NIDRR TBI Model Systems programs. Journal of Neurotrauma. 2012;29(1):59–65. doi: 10.1089/neu.2011.1829. - DOI - PubMed
    1. Stein D. G., Glasier M. M. An overview of developments in research on recovery from brain injury. In: Rose F. D., Johnson D. A., editors. Recovery from Brain Damage: Reflections and Directions. New York, NY: Plenum Press; 1992. pp. 1–22. - PubMed
    1. Foroud A., Whishaw I. Q. Changes in the kinematic structure and non-kinematic features of movements during skilled reaching after stroke: a Laban Movement Analysis in two case studies. Journal of Neuroscience Methods. 2006;158(1):137–149. doi: 10.1016/j.jneumeth.2006.05.007. - DOI - PubMed