Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jan;76(1):377-80.
doi: 10.1073/pnas.76.1.377.

Monoclonal antibodies reacting with murine teratocarcinoma cells

P N Goodfellow, J R Levinson, V E Williams 2nd, H O McDevitt

Monoclonal antibodies reacting with murine teratocarcinoma cells

P N Goodfellow et al. Proc Natl Acad Sci U S A. 1979 Jan.

Abstract

Monoclonal antibodies were produced in vitro by fusing mouse myeloma cells with spleen cells from a rat immunized with the C3H mouse teratocarcinoma C86-S1. After the fusion two clones were chosen for further analysis. The first clone, 3C4-10, produced an antibody recognizing an antigen with a distribution restricted to teratocarcinoma cell lines, an endoderm cell line, and a neuroblastoma. The second clone, 4A1-9, produced an antibody that reacted with all cultured murine cells tested and adult brain. Neither antibody reacted with preimplantation embryos. The 3C4-10 antibody recognized an antigen associated with proteins. The apparent molecular weight of the 3C4-10 antigen was greater than 100,000.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Dev Biol. 1977 Mar;56(1):157-73 - PubMed
    1. Cell. 1977 Dec;12(4):973-82 - PubMed
    1. Dev Biol. 1977 Feb;55(2):359-74 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 Jan;75(1):324-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4449-52 - PubMed

Publication types

Substances

LinkOut - more resources