Properties and uses of restriction endonucleases
- PMID: 2821353
- DOI: 10.1016/0076-6879(87)52014-6
Properties and uses of restriction endonucleases
Abstract
It is clear that we have still not exhausted all the restriction endonuclease specificities to be found in nature. Recently discovered BsmI is the first endonuclease recognizing a nonpalindromic sequence that cleaves within the site. Certainly other endonucleases belonging to this class will soon be discovered. More endonucleases are now being sought that recognize longer recognition sequences, because large fragments can now be readily separated by pulse-field electrophoresis. New sources of endonucleases are also being found; for example, a group of viruses that grow on Chlorella algae produce type II-like site-specific endonucleases. As the number and variety of known restriction endonucleases increase, the number and variety of applications keep pace. There is still no end in sight.
Similar articles
-
Digestion of DNA with restriction endonucleases.Curr Protoc Neurosci. 2001 May;Appendix 1:Appendix 1M. doi: 10.1002/0471142301.nsa01ms11. Curr Protoc Neurosci. 2001. PMID: 18428444
-
Specificity of restriction endonucleases and methylases--a review.Gene. 1986;47(1):1-153. doi: 10.1016/0378-1119(86)90245-3. Gene. 1986. PMID: 3030890 Review.
-
Recognition sequences of restriction endonucleases and methylases--a review.Gene. 1985;33(1):1-102. doi: 10.1016/0378-1119(85)90119-2. Gene. 1985. PMID: 2985469 Review.
-
Restriction endonucleases.CRC Crit Rev Biochem. 1976 Nov;4(2):123-64. doi: 10.3109/10409237609105456. CRC Crit Rev Biochem. 1976. PMID: 795607 Review.
-
Specificity of restriction endonucleases and DNA modification methyltransferases a review (Edition 3).Gene. 1990 Aug 16;92(1-2):1-248. doi: 10.1016/0378-1119(90)90486-b. Gene. 1990. PMID: 2172084 Review.
Cited by
-
Rapid shotgun cloning utilizing the two base recognition endonuclease CviJI.Nucleic Acids Res. 1992 Jul 25;20(14):3753-62. doi: 10.1093/nar/20.14.3753. Nucleic Acids Res. 1992. PMID: 1322530 Free PMC article.
-
Interpreting sperm DNA damage in a diverse range of mammalian sperm by means of the two-tailed comet assay.Front Genet. 2014 Nov 27;5:404. doi: 10.3389/fgene.2014.00404. eCollection 2014. Front Genet. 2014. PMID: 25505901 Free PMC article. Review.
-
Effect of site-specific methylation on DNA modification methyltransferases and restriction endonucleases.Nucleic Acids Res. 1989;17 Suppl(Suppl):r389-415. doi: 10.1093/nar/17.suppl.r389. Nucleic Acids Res. 1989. PMID: 2541418 Free PMC article. No abstract available.
-
Effect of site-specific methylation on restriction endonucleases and DNA modification methyltransferases.Nucleic Acids Res. 1993 Jul 1;21(13):3139-54. doi: 10.1093/nar/21.13.3139. Nucleic Acids Res. 1993. PMID: 8392715 Free PMC article. No abstract available.
-
Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases.Nucleic Acids Res. 1991 Apr 25;19 Suppl(Suppl):2045-71. doi: 10.1093/nar/19.suppl.2045. Nucleic Acids Res. 1991. PMID: 1645875 Free PMC article. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Molecular Biology Databases
Research Materials