Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Apr;115(5):619-630.
doi: 10.1002/jso.24578. Epub 2017 Feb 13.

Colorectal cancer-global burden, trends, and geographical variations

Jeffrey Douaiher  1 , Advaitaa Ravipati  2 , Benjamin Grams  1 , Sanjib Chowdhury  3 , Olusegun Alatise  4 , Chandrakanth Are  1
Affiliations

Colorectal cancer-global burden, trends, and geographical variations

Jeffrey Douaiher et al. J Surg Oncol. 2017 Apr.

Abstract

Background: The aim of this study is to describe the trends and variations in the global burden of colorectal cancer (CRC).

Methods: Data (2012-2030) relating to CRC was extracted from GLOBOCAN 2012 database and analyzed.

Results: The results of our study demonstrate a rising global burden of colorectal cancer which persists until the year 2035 and likely beyond. The rise in the global burden is not uniform with significant variations influenced by geographic location, socio-economic status, age, and gender. Although the EURO region has the highest burden, Asia as a continent continues to bear the heaviest brunt of the disease. Although the burden of disease is higher in more developed regions, mortality is considerably higher in less developed regions and this gap widens over the next two decades. The disease predominantly affects the male gender across all regions of the world. Age has a complex relation with the burden of CRC and is affected by the cross-influences relating to socio-economic status.

Conclusions: The results of our study demonstrate a rising global burden of CRC with some unique variations. Knowledge of this data can increase awareness and help strategic targeting of efforts and resources.

Keywords: colorectal cancer; epidemiology; global heath; incidence; mortality.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

LinkOut - more resources