Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017:1528:245-256.
doi: 10.1007/978-1-4939-6630-1_15.

Physarum polycephalum for Studying the Function of Histone Modifications In Vivo

Vanessa Menil-Philippot  1 , Christophe Thiriet  2
Affiliations

Physarum polycephalum for Studying the Function of Histone Modifications In Vivo

Vanessa Menil-Philippot et al. Methods Mol Biol. 2017.

Abstract

Histone modifications have been widely correlated with genetic activities. However, how these posttranslational modifications affect the dynamics and the structure of chromatin is poorly understood. Here, we describe the incorporation of the exogenous histone proteins into the slime mold Physarum polycephalum, which has been revealed to be a valuable tool for examining different facets of the function histones in chromatin dynamics like replication-coupled chromatin assembly, histone exchange, and nucleosome turnover.

Keywords: Assembly; Chromatin; Exchange; Histone modification; Nucleosome; Physarum polycephalum; Turnover.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

Publication types

MeSH terms

LinkOut - more resources