Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Oct:40:17-22.
doi: 10.1016/j.sbi.2016.06.018. Epub 2016 Jul 21.

The archiving and dissemination of biological structure data

Helen M Berman  1 , Stephen K Burley  2 , Gerard J Kleywegt  3 , John L Markley  4 , Haruki Nakamura  5 , Sameer Velankar  3
Affiliations
Review

The archiving and dissemination of biological structure data

Helen M Berman et al. Curr Opin Struct Biol. 2016 Oct.

Abstract

The global Protein Data Bank (PDB) was the first open-access digital archive in biology. The history and evolution of the PDB are described, together with the ways in which molecular structural biology data and information are collected, curated, validated, archived, and disseminated by the members of the Worldwide Protein Data Bank organization (wwPDB; http://wwpdb.org). Particular emphasis is placed on the role of community in establishing the standards and policies by which the PDB archive is managed day-to-day.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Growth of the PDB archive. A) Number of entries deposited annually (dark grey) and available at the end of each year (light grey); B) number of X-ray crystal structures, C) NMR structures, and D) 3DEM structures available each year.
Figure 2
Figure 2
wwPDB Deposition, Annotation, and Validation pipeline. Each box represents a modular component of the data processing workflow.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bernal JD, Crowfoot DM. X-ray photographs of crystalline pepsin. Nature. 1934;133:794–795.
    1. Kendrew JC, Bodo G, Dintzis HM, Parrish RG, Wyckoff H, Phillips DC. A threedimensional model of the myoglobin molecule obtained by x-ray analysis. Nature. 1958;181:662–666. - PubMed
    1. Kendrew JC, Dickerson RE, Strandberg BE, Hart RG, Davies DR, Phillips DC, Shore VC. Structure of myoglobin: A three-dimensional Fourier synthesis at 2 A. resolution. Nature. 1960;185:422–427. - PubMed
    1. Perutz MF, Rossmann MG, Cullis AF, Muirhead H, Will G, North ACT. Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5 Å resolution, obtained by X-ray analysis. Nature. 1960;185:416–422. - PubMed
    1. Bolton W, Perutz MF. Three dimensional fourier synthesis of horse deoxyhaemoglobin at 2.8 Ångstrom units resolution. Nature. 1970;228:551–552. - PubMed

Publication types

LinkOut - more resources