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. 2016 Oct;22(10):1843-1846.
doi: 10.3201/eid2210.160357. Epub 2016 Oct 15.

Recombinant Enterovirus A71 Subgenogroup C1 Strains, Germany, 2015

Collaborators

Recombinant Enterovirus A71 Subgenogroup C1 Strains, Germany, 2015

Sindy Böttcher et al. Emerg Infect Dis. 2016 Oct.
No abstract available

Keywords: Germany; acute flaccid paralysis; enterovirus; enterovirus A71; meningitis; picornavirus; surveillance; viruses.

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Figures

Figure
Figure
Phylogenetic tree based on complete viral protein 1 (VP1) nucleotide sequences of the strains identified within the German enterovirus surveillance (bold) and a representative set of enterovirus A71 strains available from GenBank (891 bases, corresponding to nucleotide positions 2439–3329 in the prototype BrCr ETU22521). The tree was constructed by using the neighbor-joining method (Kimura 2-parameter model) with 1,000 replicates through MEGA 6.06 (http://www.megasoftware.net/). Coxsackievirus A16 prototype (CAU05876) was used as the outgroup. Only bootstrap values >70 are shown. Genogroup and subgenogroup assignment, GenBank accession number, country and year of isolation are provided in the virus names. The enlarged subtree includes enterovirus A71 C1-like strains detected in Germany in 2015. Virus names contain strain number, abbreviation of federal state, country, and year of isolation. BE, Berlin; BB, Brandenburg; DE, Germany; MV, Mecklenburg Western Pomerania; NI, Lower Saxony; NW, Northrhine-Westphalia; RP, Rhineland Palatinate; TH, Thuringia. Scale bars indicate nucleotide substitution per site.

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References

    1. Yip CC, Lau SK, Woo PC, Yuen KY. Human enterovirus 71 epidemics: what’s next? Emerg Health Threats J. 2013;6:19780. 10.3402/ehtj.v6i0.19780 - DOI - PMC - PubMed
    1. Brown BA, Oberste MS, Alexander JP Jr, Kennett ML, Pallansch MA. Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998. J Virol. 1999;73:9969–75. - PMC - PubMed
    1. McMinn PC. Recent advances in the molecular epidemiology and control of human enterovirus 71 infection Curr Opin Virol. 2012;2:199–205. 10.1016/j.coviro.2012.02.009 - DOI - PubMed
    1. Saxena VK, Sane S, Nadkarni SS, Sharma DK, Deshpande JM. Genetic diversity of enterovirus A71, India. Emerg Infect Dis. 2015;21:123–6. - PMC - PubMed
    1. Bessaud M, Razafindratsimandresy R, Nougairède A, Joffret ML, Deshpande JM, Dubot-Pérès A, et al. Molecular comparison and evolutionary analyses of VP1 nucleotide sequences of new African human enterovirus 71 isolates reveal a wide genetic diversity. PLoS One. 2014;9:e90624. 10.1371/journal.pone.0090624 - DOI - PMC - PubMed

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