A roadmap for MERS-CoV research and product development: report from a World Health Organization consultation
- PMID: 27387881
- PMCID: PMC7096003
- DOI: 10.1038/nm.4131
A roadmap for MERS-CoV research and product development: report from a World Health Organization consultation
Abstract
As part of the World Health Organization (WHO) R&D Blueprint initiative, leading stakeholders on Middle East respiratory syndrome coronavirus (MERS-CoV) convened to agree on strategic public-health goals and global priority research activities that are needed to combat MERS-CoV.
Supplementary information: The online version of this article (doi:10.1038/nm.4131) contains supplementary material, which is available to authorized users.
Conflict of interest statement
X.W. has a patent pending regarding peptides inhibiting TDP-43 mitochondrial localization.
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References
-
- WHO. http://www.who.int/csr/disease/coronavirus_infections/MERS-CoV_summary_u... (World Health Organization, Geneva, 2014).
-
- Cohen J. Science. 2016;351:16–19. - PubMed
-
- Ben Embarek PK, Van Kerkhove MD. Wkly. Epidemiol. Rec. 2015;90:245–250. - PubMed
-
- Drosten C, et al. Clin. Infect. Dis. 2015;60:369–377. - PubMed
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