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Review
. 2016 Jul 6;98(13):1132-9.
doi: 10.2106/JBJS.16.00299.

Tissue Engineering in Orthopaedics

Alexander M Tatara  1 , Antonios G Mikos  2
Affiliations
Review

Tissue Engineering in Orthopaedics

Alexander M Tatara et al. J Bone Joint Surg Am. .

Abstract

➤It is important to carefully select the most appropriate combination of scaffold, signals, and cell types when designing tissue engineering approaches for an orthopaedic pathology.➤Although clinical studies in which the tissue engineering paradigm has been applied in the treatment of orthopaedic diseases are limited in number, examining them can yield important lessons.➤While there is a rapid rate of new discoveries in the basic sciences, substantial regulatory, economic, and clinical issues must be overcome with more consistency to translate a greater number of technologies from the laboratory to the operating room.

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Figures

Fig. 1
Fig. 1
The orthopaedic tissue engineering paradigm.
Fig. 2
Fig. 2
Overview of the classes of scaffolds.
See this image and copyright information in PMC

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