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Review
. 2016 Jul;30(3):119-43.
doi: 10.1016/j.trre.2016.04.001. Epub 2016 Apr 29.

Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

J Torre-Cisneros  1 , J M Aguado  2 , J J Caston  3 , L Almenar  4 , A Alonso  5 , S Cantisán  6 , J Carratalá  7 , C Cervera  8 , E Cordero  9 , M C Fariñas  10 , M Fernández-Ruiz  11 , J Fortún  12 , E Frauca  13 , J Gavaldá  14 , D Hernández  15 , I Herrero  16 , O Len  14 , F Lopez-Medrano  11 , N Manito  17 , M A Marcos  18 , P Martín-Dávila  19 , V Monforte  20 , M Montejo  21 , A Moreno  22 , P Muñoz  23 , D Navarro  24 , P Pérez-Romero  25 , A Rodriguez-Bernot  26 , J Rumbao  27 , R San Juan  28 , J M Vaquero  29 , E Vidal  30 ; Spanish Society of Transplantation (SET); Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases and Clinical Microbiology (GESITRA-SEIMC); Spanish Network for Research in Infectious Diseases (REIPI)
Affiliations
Review

Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

J Torre-Cisneros et al. Transplant Rev (Orlando). 2016 Jul.

Abstract

Cytomegalovirus (CMV) infection remains a major complication of solid organ transplantation. Because of management of CMV is variable among transplant centers, in 2011 the Spanish Transplantation Infection Study Group (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) developed consensus guidelines for the prevention and treatment of CMV infection in solid organ transplant recipients. Since then, new publications have clarified or questioned the aspects covered in the previous document. For that reason, a panel of experts revised the evidence on CMV management, including immunological monitoring, diagnostics, prevention, vaccines, indirect effects, treatment, drug resistance, immunotherapy, investigational drugs, and pediatric issues. This document summarizes the recommendations.

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