To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

doi:10.1016/j.stem.2015.12.004

. 2016 Jan 7;18(1):13-5.

doi: 10.1016/j.stem.2015.12.004.

To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

Jason A Burdick¹, Robert L Mauck², Sharon Gerecht³

Affiliations

¹ Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: burdick2@seas.upenn.edu.
² Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
³ Department of Chemical and Biomolecular Engineering and the Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.

PMID: 26748751
DOI: 10.1016/j.stem.2015.12.004

Free article

To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

Jason A Burdick et al. Cell Stem Cell. 2016.

Free article

. 2016 Jan 7;18(1):13-5.

doi: 10.1016/j.stem.2015.12.004.

Authors

Jason A Burdick¹, Robert L Mauck², Sharon Gerecht³

Affiliations

¹ Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: burdick2@seas.upenn.edu.
² Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
³ Department of Chemical and Biomolecular Engineering and the Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.

PMID: 26748751
DOI: 10.1016/j.stem.2015.12.004

Abstract

Harsh environments within damaged and diseased tissues and limited retention and survival of injected stem cells pose major challenges for stem cell therapeutics today. Here, we discuss promising hydrogel-based strategies for improving engraftment and viability of transplanted stem cells and stimulating recruitment of endogenous stem cells for repair.

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To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

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To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

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