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. 2016 May;25(5):340-3.
doi: 10.1111/exd.12935. Epub 2016 Feb 26.

Are itch and scratching the nausea and vomiting of skin?

Sattar Ostadhadi  1   2   3 , Ehsan Azimi  4 , Ethan A Lerner  4 , Ahmad-Reza Dehpour  1   2   3
Affiliations

Are itch and scratching the nausea and vomiting of skin?

Sattar Ostadhadi et al. Exp Dermatol. 2016 May.

Abstract

The physiologic similarities between itch and nausea may not be evident initially, but they share the role of repelling irritants and toxins from the body by inducting scratching and vomiting, respectively. In addition, itch and nausea frequently occur together in certain conditions such as uraemia. Here we show that the mechanisms underlying itch and nausea overlap and that advances in either field may influence the identification of novel drug targets, particularly for itch.

Keywords: itch; nausea; scratching; vomiting.

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Conflict of interest statement

Conflict of interests

The authors have declared no conflicting interests.

Comment in

  • The gut-itch connection.
    Sanders KM, Nattkemper LA, Yosipovitch G. Sanders KM, et al. Exp Dermatol. 2016 May;25(5):344-5. doi: 10.1111/exd.12994. Exp Dermatol. 2016. PMID: 26914808 No abstract available.

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