Abdominal metastases from colorectal cancer: intraperitoneal therapy

doi:10.3978/j.issn.2078-6891.2015.078

Review

. 2015 Dec;6(6):693-8.

doi: 10.3978/j.issn.2078-6891.2015.078.

Abdominal metastases from colorectal cancer: intraperitoneal therapy

Hamza Guend¹, Sunil Patel¹, Garrett M Nash¹

Affiliations

PMID: 26697203
PMCID: PMC4671857
DOI: 10.3978/j.issn.2078-6891.2015.078

Review

Abdominal metastases from colorectal cancer: intraperitoneal therapy

Hamza Guend et al. J Gastrointest Oncol. 2015 Dec.

. 2015 Dec;6(6):693-8.

doi: 10.3978/j.issn.2078-6891.2015.078.

Authors

Hamza Guend¹, Sunil Patel¹, Garrett M Nash¹

Affiliation

¹ Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

PMID: 26697203
PMCID: PMC4671857
DOI: 10.3978/j.issn.2078-6891.2015.078

Abstract

Patients with peritoneal metastasis from colorectal cancer represent a distinct subset with regional disease rather than systemic disease. They often have poorer survival outcomes with systemic chemotherapy. Optimal cytoreductive surgery and intraperitoneal chemotherapy (IPC) offers such patients a more directed therapy with improved survival. In this review, we discuss the diagnosis, evaluation and classification, as well as rational for treatment of peritoneal carcinomatosis (PC) secondary to colorectal cancer.

Keywords: Colorectal peritoneal carcinomatosis (PC); cytoreductive surgery; intraperitoneal chemotherapy (IPC).

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Conflict of interest statement

Conflicts of interest: The authors have no conflicts of interest to declare.

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References

1. van Gestel YR, de Hingh IH, van Herk-Sukel MP, et al. Patterns of metachronous metastases after curative treatment of colorectal cancer. Cancer Epidemiol 2014;38:448-54. - PubMed
1. Segelman J, Granath F, Holm T, et al. Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer. Br J Surg 2012;99:699-705. - PubMed
1. Chua TC, Liauw W, Chu F, et al. Viewing metastatic colorectal cancer as a curable chronic disease. Am J Clin Oncol 2012;35:77-80. - PubMed
1. Klaver YL, Simkens LH, Lemmens VE, et al. Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy. Eur J Surg Oncol 2012;38:617-23. - PubMed
1. Franko J, Shi Q, Goldman CD, et al. Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. J Clin Oncol 2012;30:263-7. - PMC - PubMed

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[1] van Gestel YR, de Hingh IH, van Herk-Sukel MP, et al. Patterns of metachronous metastases after curative treatment of colorectal cancer. Cancer Epidemiol 2014;38:448-54. - PubMed

[2] van Gestel YR, de Hingh IH, van Herk-Sukel MP, et al. Patterns of metachronous metastases after curative treatment of colorectal cancer. Cancer Epidemiol 2014;38:448-54. - PubMed

[3] Segelman J, Granath F, Holm T, et al. Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer. Br J Surg 2012;99:699-705. - PubMed

[4] Segelman J, Granath F, Holm T, et al. Incidence, prevalence and risk factors for peritoneal carcinomatosis from colorectal cancer. Br J Surg 2012;99:699-705. - PubMed

[5] Chua TC, Liauw W, Chu F, et al. Viewing metastatic colorectal cancer as a curable chronic disease. Am J Clin Oncol 2012;35:77-80. - PubMed

[6] Chua TC, Liauw W, Chu F, et al. Viewing metastatic colorectal cancer as a curable chronic disease. Am J Clin Oncol 2012;35:77-80. - PubMed

[7] Klaver YL, Simkens LH, Lemmens VE, et al. Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy. Eur J Surg Oncol 2012;38:617-23. - PubMed

[8] Klaver YL, Simkens LH, Lemmens VE, et al. Outcomes of colorectal cancer patients with peritoneal carcinomatosis treated with chemotherapy with and without targeted therapy. Eur J Surg Oncol 2012;38:617-23. - PubMed

[9] Franko J, Shi Q, Goldman CD, et al. Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. J Clin Oncol 2012;30:263-7. - PMC - PubMed

[10] Franko J, Shi Q, Goldman CD, et al. Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. J Clin Oncol 2012;30:263-7. - PMC - PubMed

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Abdominal metastases from colorectal cancer: intraperitoneal therapy

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Abdominal metastases from colorectal cancer: intraperitoneal therapy

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