Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Oct;29(5):479-80, 482-5.
doi: 10.1007/s00482-015-0028-y.

[Neuropathic pain. How to open the blackbox]

[Article in German]
C Maier  1 , R Baron  2 , C Sommer  3
Affiliations
Review

[Neuropathic pain. How to open the blackbox]

[Article in German]
C Maier et al. Schmerz. 2015 Oct.

Abstract

This article, without presuming to be comprehensive, gives a brief outline of the development of research on neuropathic pain in Germany. Current clinical research on this subject focusses on the validation of human models, patient phenotyping, mechanism-based classification and treatment as well as on molecular pathomechanisms. This clinical research is based to a large extent on the work of several internationally recognized basic researchers in the 1990s. In particular, findings from system physiology led to the analysis of clinical phenotypes and the underlying pathophysiology. In parallel, basic research achieved international top levels through the development of innovative methods. Close cooperation, building of consortia and European networking made major contributions to the success of this research.

Keywords: Mechanism-based treatment; Models, animal; Neuroinflammation; Systems physiology; Translational medical research.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Prog Brain Res. 2000;129:331-41 - PubMed
    1. Pain. 2012 Feb;153(2):420-8 - PubMed
    1. Pain. 2011 Sep;152(9):2138-46 - PubMed
    1. Science. 2012 Jan 13;335(6065):235-8 - PubMed
    1. Lancet. 2003 Feb 22;361(9358):690-4 - PubMed

LinkOut - more resources