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Review
. 2015 Jul 30;12(8):8871-82.
doi: 10.3390/ijerph120808871.

Infection Control Programs and Antibiotic Control Programs to Limit Transmission of Multi-Drug Resistant Acinetobacter baumannii Infections: Evolution of Old Problems and New Challenges for Institutes

Chang-Hua Chen  1   2 , Li-Chen Lin  3 , Yu-Jun Chang  4 , Yu-Min Chen  5 , Chin-Yen Chang  6 , Chieh-Chen Huang  7
Affiliations
Review

Infection Control Programs and Antibiotic Control Programs to Limit Transmission of Multi-Drug Resistant Acinetobacter baumannii Infections: Evolution of Old Problems and New Challenges for Institutes

Chang-Hua Chen et al. Int J Environ Res Public Health. .

Abstract

Background: Acinetobacter baumannii complex (A. baumannii) has been isolated worldwide. The rapid spread of multidrug-resistant A. baumannii complex (MDRAB) in clinical settings has made choosing an appropriate antibiotic to treat these infections and executing contact precautions difficult for clinicians. Although controlling the transmission of MDRAB is a high priority for institutions, there is little information about MDRAB control. Therefore, this study evaluated infection control measures for A. baumannii infections, clusters and outbreaks in the literature.

Methods: We performed a review of OVID Medline (from 1980 to 2015), and analyzed the literature.

Results: We propose that both infection control programs and antibiotic control programs are essential for control of MDRAB. The first, effective control of MDRAB infections, requires compliance with a series of infection control methods including strict environmental cleaning, effective sterilization of reusable medical equipment, concentration on proper hand hygiene practices, and use of contact precautions, together with appropriate administrative guidance. The second strategy, effective antibiotic control programs to decrease A. baumannii, is also of paramount importance.

Conclusion: We believe that both infection control programs and antibiotics stewardship programs are essential for control of MDRAB infections.

Keywords: Acinetobacter baumannii complex; antibiotic control programs; infection control programs; multidrug-resistant.

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Figures

Figure 1
Figure 1
Risk factors for acquisition of A. baumannii infections (including acquisition of multi-drug-resistant A. baumannii). The acquisition of A. baumannii infections include three factors, which are source, host, and transmission. The reference number of those reported risk factors is marked between open parenthesis and close parenthesis; carbepenem resistant A. baumannii (CRAB); MDRAB: multidrug-resistant A. baumannii.
Figure 2
Figure 2
Summary of infection control measures directed against A. baumannii outbreak and cluster; the infection control measures for A. baumannii outbreak and cluster are summarized. The literature number of those reported risk factors is marked between open parenthesis and close parentheses.
See this image and copyright information in PMC

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