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Comment
. 2015 Jul 27;212(8):1140-1.
doi: 10.1084/jem.2128insight2.

Saving β cell function in the NIK of time

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Comment

Saving β cell function in the NIK of time

Kristin V Tarbell et al. J Exp Med. .
No abstract available

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Insight from Kristin Tarbell (left) and Sushil Rane (right)
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β cell–specific TRAF2 knockout mice (βTRAF2 mice) have β cell–intrinsic NIK activation. In a diet-induced obesity model, βTRAF2 mice demonstrate exacerbated glucose intolerance compared with wild-type mice.

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References

    1. Malle, E.K., et al. . 2015. J. Exp. Med. 10.1084/jem.20150218 - DOI - PubMed

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