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. 2015 Feb;8(1.5):S4-S11.

High survival rates and associated factors among ebola virus disease patients hospitalized at donka national hospital, conakry, Guinea

Adnan I Qureshi  1 , Morad Chughtai  1 , Elhadj Ibrahima Bah  2 , Moumié Barry  3 , Kézély Béavogui  4 , Tokpagnan Oscar Loua  5 , Ahmed A Malik  1
Affiliations

High survival rates and associated factors among ebola virus disease patients hospitalized at donka national hospital, conakry, Guinea

Adnan I Qureshi et al. J Vasc Interv Neurol. 2015 Feb.

Abstract

Background: Anecdotal reports suggesting that survival rates among hospitalized patients with Ebola virus disease in Guinea are higher than the 29.2% rate observed in the current epidemic in West Africa.

Methods: Survival after symptom onset was determined using Kaplan Meier survival methods among patients with confirmed Ebola virus disease treated in Conakry, Guinea from March 25, 2014, to August 5, 2014. We analyzed the relationship between survival and patient factors, including demographics and clinical features.

Results: Of the 70 patients analyzed [mean age ± standard deviation (SD), 34 ± 14.1; 44 were men], 42 were discharged alive with a survival rate among hospitalized patients of 60% (95% confidence interval, 41.5-78.5%). The survival rate was 28 (71.8%) among 39 patients under 34 years of age, and 14 (46.7%) among 30 patients aged 35 years or greater (p = 0.034). The rates of myalgia (3 of 42 versus 7 of 28, p = 0.036) and hiccups (1 of 42 versus 5 of 28, p = 0.023) were significantly lower among patients who survived.

Conclusions: Our results provide insights into a cohort of hospitalized patients with Ebola virus disease in whom survival is prominently higher than seen in other cohorts of hospitalized patients.

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Figures

Figure 1
Figure 1. Survival of patients with Ebola virus disease after first day of hospitalization according to age strata. Solid line: survival among patients aged <35 years. Dashed line: survival among those aged 35 years or greater.
Figure 2
Figure 2. Survival of patients with Ebola virus disease after first day of hospitalization according to the presence or absence of hiccups or myalgias. Solid line: survival among patients who did not develop either symptom. Dashed line: survival among those developed either hiccups or myalgias.
Figure 3
Figure 3. Proportion of patients with Ebola virus disease surviving according to time interval elapsed between symptom onset and day of discharge. Black and white components of the vertical bar represent proportion of patients who died or survived according to days past symptom onset, respectively.
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