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. 2015 May 7;3(3):e00403-15.
doi: 10.1128/genomeA.00403-15.

Draft Genome Sequence of Mycobacterium tuberculosis Strain E186hv of Beijing B0/W Lineage with Reduced Virulence

K V Shur  1 , K M Klimina  1 , N V Zakharevich  1 , D A Maslov  1 , O B Bekker  1 , M V Zaychikova  1 , E Y Kamaev  2 , M A Kravchenko  2 , S N Skornyakov  2 , Y Zhang  3 , V N Danilenko  4
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Draft Genome Sequence of Mycobacterium tuberculosis Strain E186hv of Beijing B0/W Lineage with Reduced Virulence

K V Shur et al. Genome Announc. .

Abstract

We report a draft genome sequence of Mycobacterium tuberculosis strain E186hv, belonging to the Beijing B0/W lineage and isolated from a patient from Kurgan, Russia. This clinical isolate showed a reduced virulence phenotype unusual for this lineage and resistance to isoniazid, rifampin, ethambutol, pyrazinamide, and ofloxacin. We analyzed single nucleotide polymorphisms (SNPs) associated with virulence.

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