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. 2015 Apr;21(4):646-9.
doi: 10.3201/eid2104.140734.

La Crosse Virus in Aedes japonicus japonicus mosquitoes in the Appalachian Region, United States

M Camille Harris, Eric J Dotseth, Bryan T Jackson, Steven D Zink, Paul E Marek, Laura D Kramer, Sally L Paulson, Dana M Hawley

La Crosse Virus in Aedes japonicus japonicus mosquitoes in the Appalachian Region, United States

M Camille Harris et al. Emerg Infect Dis. 2015 Apr.

Abstract

La Crosse virus (LACV), a leading cause of arboviral encephalitis in children in the United States, is emerging in Appalachia. For local arboviral surveillance, mosquitoes were tested. LACV RNA was detected and isolated from Aedes japonicus mosquitoes. These invasive mosquitoes may significantly affect LACV range expansion and dynamics.

Keywords: Aedes japonicus; Appalachian region; La Crosse virus; United States; Virginia; West Virginia; disease vector; mosquitoes; vector-borne infections; viruses.

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Figures

Figure 1
Figure 1
Locations of detection of La Crosse virus (LACV) RNA and virus isolation from Aedes japonicus mosquito pools. The red stars represent counties of the Ae. japonicus LACV isolates, and the blue stars represent counties of Ae. japonicus LACV RNA detection.
Figure 2
Figure 2
Phylogeny of La Crosse virus (LACV) based on the medium (M) segment of the viral polyprotein gene. State of isolate origin, isolation year, mosquito, or vertebrate isolate source and the National Center for Biotechnology Information (NCBI) accession numbers are listed for each isolate within the tree. The scale bar represents the number of nucleotide substitutions per site. LACV historical lineages are identified by vertical bars. The 2009 isolates from Virginia (NCBI accession nos. KP226847, KP226848) group with lineage 1 viruses. Ae., Aedes; Ps., Psorophora.
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