On-label and off-label drug use in the treatment of female infertility
- PMID: 25660647
- DOI: 10.1016/j.fertnstert.2015.01.011
On-label and off-label drug use in the treatment of female infertility
Abstract
Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. The purpose of this article is to review the uses of both off-label treatments and those approved by the US Food and Drug Administration for female infertility, by examining the mechanism of action, the side-effect profile, fetal anomaly risks, and contraindications for the various drugs.
Keywords: Female infertility; medications for female infertility.
Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Similar articles
-
Therapy: Unexplained infertility - ongoing transatlantic debate.Nat Rev Endocrinol. 2016 Jan;12(1):8-10. doi: 10.1038/nrendo.2015.200. Epub 2015 Nov 20. Nat Rev Endocrinol. 2016. PMID: 26585663 No abstract available.
-
On-label and off-label drugs used in the treatment of male infertility.Fertil Steril. 2015 Mar;103(3):595-604. doi: 10.1016/j.fertnstert.2014.12.122. Epub 2015 Feb 3. Fertil Steril. 2015. PMID: 25660648 Review.
-
Fewer live births occur with letrozole than standard therapy for unexplained infertility, study shows.BMJ. 2015 Sep 24;351:h5070. doi: 10.1136/bmj.h5070. BMJ. 2015. PMID: 26407841 No abstract available.
-
Drugs for ovulation induction.Med Lett Drugs Ther. 2011 Oct 31;53(1376):86-8. Med Lett Drugs Ther. 2011. PMID: 22033212
-
Endocrine and reproductive effects of polycystic ovarian syndrome.Obstet Gynecol Clin North Am. 2015 Mar;42(1):55-65. doi: 10.1016/j.ogc.2014.09.003. Epub 2014 Dec 13. Obstet Gynecol Clin North Am. 2015. PMID: 25681840 Review.
Cited by
-
Novel compound heterozygous mutations in WEE2 causes female infertility and fertilization failure.J Assist Reprod Genet. 2019 Sep;36(9):1957-1962. doi: 10.1007/s10815-019-01553-3. Epub 2019 Aug 19. J Assist Reprod Genet. 2019. PMID: 31428887 Free PMC article.
-
Chinese medicine as complementary therapy for female infertility.Chin J Integr Med. 2017 Apr;23(4):245-252. doi: 10.1007/s11655-016-2510-5. Epub 2016 Aug 2. Chin J Integr Med. 2017. PMID: 27484764 Review.
-
Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis.BMJ. 2017 Jan 31;356:j138. doi: 10.1136/bmj.j138. BMJ. 2017. PMID: 28143834 Free PMC article. Review.
-
Cancer Risk in Women Treated with Fertility Drugs According to Parity Status-A Registry-based Cohort Study.Cancer Epidemiol Biomarkers Prev. 2017 Jun;26(6):953-962. doi: 10.1158/1055-9965.EPI-16-0809. Epub 2017 Jan 20. Cancer Epidemiol Biomarkers Prev. 2017. PMID: 28108444 Free PMC article.
-
A comparison of oral versus injectable ovarian stimulation in IUI in women ≥38 years of age with decreased ovarian reserve.Arch Gynecol Obstet. 2021 Jun;303(6):1607-1616. doi: 10.1007/s00404-020-05897-5. Epub 2021 Jan 3. Arch Gynecol Obstet. 2021. PMID: 33389112
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical