doi: 10.1016/0042-6822(89)90062-7.
The bovine papillomavirus type 1 transcriptional activator E2 protein binds to its DNA recognition sequence as a dimer
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- PMID: 2538035
- DOI: 10.1016/0042-6822(89)90062-7
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The bovine papillomavirus type 1 transcriptional activator E2 protein binds to its DNA recognition sequence as a dimer
Virology.
1989 Mar.
Abstract
The transcriptional trans-activator E2 protein from bovine papillomavirus type 1 has been shown to bind to the DNA consensus sequence ACCN6GGT. We have produced the DNA-binding domain of the E2 protein as a recombinant protein in Escherichia coli. The E2 DNA-binding domain was purified as two different molecular weight forms. Using these purified proteins, we show that two molecules of the E2 protein bind to a single DNA consensus binding site.
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