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Review
. 2014 Aug 26;2014(8):CD011275.
doi: 10.1002/14651858.CD011275.

Manual therapy and exercise for adhesive capsulitis (frozen shoulder)

Matthew J Page  1 , Sally Green, Sharon Kramer, Renea V Johnston, Brodwen McBain, Marisa Chau, Rachelle Buchbinder
Affiliations
Review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder)

Matthew J Page et al. Cochrane Database Syst Rev. .

Abstract

Background: Adhesive capsulitis (also termed frozen shoulder) is commonly treated by manual therapy and exercise, usually delivered together as components of a physical therapy intervention. This review is one of a series of reviews that form an update of the Cochrane review, 'Physiotherapy interventions for shoulder pain.'

Objectives: To synthesise available evidence regarding the benefits and harms of manual therapy and exercise, alone or in combination, for the treatment of patients with adhesive capsulitis.

Search methods: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, CINAHL Plus, ClinicalTrials.gov and the WHO ICTRP clinical trials registries up to May 2013, unrestricted by language, and reviewed the reference lists of review articles and retrieved trials, to identify potentially relevant trials.

Selection criteria: We included randomised controlled trials (RCTs) and quasi-randomised trials, including adults with adhesive capsulitis, and comparing any manual therapy or exercise intervention versus placebo, no intervention, a different type of manual therapy or exercise or any other intervention. Interventions included mobilisation, manipulation and supervised or home exercise, delivered alone or in combination. Trials investigating the primary or adjunct effect of a combination of manual therapy and exercise were the main comparisons of interest. Main outcomes of interest were participant-reported pain relief of 30% or greater, overall pain (mean or mean change), function, global assessment of treatment success, active shoulder abduction, quality of life and the number of participants experiencing adverse events.

Data collection and analysis: Two review authors independently selected trials for inclusion, extracted the data, performed a risk of bias assessment and assessed the quality of the body of evidence for the main outcomes using the GRADE approach.

Main results: We included 32 trials (1836 participants). No trial compared a combination of manual therapy and exercise versus placebo or no intervention. Seven trials compared a combination of manual therapy and exercise versus other interventions but were clinically heterogeneous, so opportunities for meta-analysis were limited. The overall impression gained from these trials is that the few outcome differences between interventions that were clinically important were detected only up to seven weeks. Evidence of moderate quality shows that a combination of manual therapy and exercise for six weeks probably results in less improvement at seven weeks but a similar number of adverse events compared with glucocorticoid injection. The mean change in pain with glucocorticoid injection was 58 points on a 100-point scale, and 32 points with manual therapy and exercise (mean difference (MD) 26 points, 95% confidence interval (CI) 15 points to 37 points; one RCT, 107 participants), for an absolute difference of 26% (15% to 37%). Mean change in function with glucocorticoid injection was 39 points on a 100-point scale, and 14 points with manual therapy and exercise (MD 25 points, 95% CI 35 points to 15 points; one RCT, 107 participants), for an absolute difference of 25% (15% to 35%). Forty-six per cent (26/56) of participants reported treatment success with manual therapy and exercise compared with 77% (40/52) of participants receiving glucocorticoid injection (risk ratio (RR) 0.6, 95% CI 0.44 to 0.83; one RCT, 108 participants), with an absolute risk difference of 30% (13% to 48%). The number reporting adverse events did not differ between groups: 56% (32/57) reported events with manual therapy and exercise, and 53% (30/57) with glucocorticoid injection (RR 1.07, 95% CI 0.76 to 1.49; one RCT, 114 participants), with an absolute risk difference of 4% (-15% to 22%). Group differences in improvement in overall pain and function at six months and 12 months were not clinically important.We are uncertain of the effect of other combinations of manual therapy and exercise, as most evidence is of low quality. Meta-analysis of two trials (86 participants) suggested no clinically important differences between a combination of manual therapy, exercise, and electrotherapy for four weeks and placebo injection compared with glucocorticoid injection alone or placebo injection alone in terms of overall pain, function, active range of motion and quality of life at six weeks, six months and 12 months (though the 95% CI suggested function may be better with glucocorticoid injection at six weeks). The same two trials found that adding a combination of manual therapy, exercise and electrotherapy for four weeks to glucocorticoid injection did not confer clinically important benefits over glucocorticoid injection alone at each time point. Based on one high quality trial (148 participants), following arthrographic joint distension with glucocorticoid and saline, a combination of manual therapy and supervised exercise for six weeks conferred similar effects to those of sham ultrasound in terms of overall pain, function and quality of life at six weeks and at six months, but provided greater patient-reported treatment success and active shoulder abduction at six weeks. One trial (119 participants) found that a combination of manual therapy, exercise, electrotherapy and oral non-steroidal anti-inflammatory drug (NSAID) for three weeks did not confer clinically important benefits over oral NSAID alone in terms of function and patient-reported treatment success at three weeks.On the basis of 25 clinically heterogeneous trials, we are uncertain of the effect of manual therapy or exercise when not delivered together, or one type of manual therapy or exercise versus another, as most reported differences between groups were not clinically or statistically significant, and the evidence is mostly of low quality.

Authors' conclusions: The best available data show that a combination of manual therapy and exercise may not be as effective as glucocorticoid injection in the short-term. It is unclear whether a combination of manual therapy, exercise and electrotherapy is an effective adjunct to glucocorticoid injection or oral NSAID. Following arthrographic joint distension with glucocorticoid and saline, manual therapy and exercise may confer effects similar to those of sham ultrasound in terms of overall pain, function and quality of life, but may provide greater patient-reported treatment success and active range of motion. High-quality RCTs are needed to establish the benefits and harms of manual therapy and exercise interventions that reflect actual practice, compared with placebo, no intervention and active interventions with evidence of benefit (e.g. glucocorticoid injection).

PubMed Disclaimer

Conflict of interest statement

SG and RB are authors of one of the trials included in this review (Buchbinder 2007). To avoid bias, this paper was sent to an independent review author for assessment of whether it met the inclusion criteria for this review. Neither review author was involved in data extraction or risk of bias assessment for this trial. RB is Joint Co‐ordinating Editor and RJ is Managing Editor of the Cochrane Musculoskeletal Group. To avoid bias, they excluded themselves from the editorial and publication processes for this review. SG and BMcB are practicing physiotherapists in part‐time private physiotherapy practice (self employed) and in this role receive remuneration for the delivery of physiotherapy interventions.

Figures

1
1
Study flow diagram.
2
2
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies. Note that the white areas in "Blinding of outcome assessment (detection bias): self‐reported outcomes" and "Blinding of outcome assessment (detection bias): objective outcomes" indicate that the domain was not applicable to all trials because some trials did not measure any self‐reported or objective outcomes, respectively.
3
3
Risk of bias summary: review authors' judgements about each risk of bias item for each included study. Note that white squares indicate that the domain was not applicable to the trial, because no self‐reported or objective outcomes, respectively, were measured in the trial.
1.1
1.1. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 1 Overall pain.
1.2
1.2. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 2 Function.
1.3
1.3. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 3 Quality of life.
1.4
1.4. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 4 Active range of motion (degrees).
1.5
1.5. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 5 Active range of motion (cm).
1.6
1.6. Analysis
Comparison 1 Manual therapy plus exercise plus electrotherapy plus placebo injection versus glucocorticoid injection, Outcome 6 Passive range of motion.
2.1
2.1. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 1 Overall pain.
2.2
2.2. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 2 Function.
2.3
2.3. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 3 Quality of life.
2.4
2.4. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 4 Active range of motion (degrees).
2.5
2.5. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 5 Active range of motion (cm).
2.6
2.6. Analysis
Comparison 2 Manual therapy plus exercise plus electrotherapy plus placebo injection versus placebo injection, Outcome 6 Passive range of motion.
3.1
3.1. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 1 Overall pain.
3.2
3.2. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 2 Function.
3.3
3.3. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 3 Quality of life.
3.4
3.4. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 4 Active range of motion (degrees).
3.5
3.5. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 5 Active range of motion (cm).
3.6
3.6. Analysis
Comparison 3 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus glucocorticoid injection, Outcome 6 Passive range of motion.
4.1
4.1. Analysis
Comparison 4 Anterior glide mobilisation plus ultrasound plus exercises versus posterior glide mobilisation plus ultrasound plus exercises, Outcome 1 Overall pain (VAS 0‐10).
4.2
4.2. Analysis
Comparison 4 Anterior glide mobilisation plus ultrasound plus exercises versus posterior glide mobilisation plus ultrasound plus exercises, Outcome 2 Active range of motion.
5.1
5.1. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 1 Overall pain.
5.2
5.2. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 2 Function.
5.3
5.3. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 3 Quality of life.
5.4
5.4. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 4 Active range of motion (degrees).
5.5
5.5. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 5 Active range of motion (cm).
5.6
5.6. Analysis
Comparison 5 Manual therapy plus exercise plus electrotherapy plus glucocorticoid injection versus placebo injection, Outcome 6 Passive range of motion.
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References

References to studies included in this review

Buchbinder 2007 {published data only}
    1. Buchbinder R, Youd JM, Green S, Stein A, Forbes A, Harris A, et al. Efficacy and cost‐effectiveness of physiotherapy following glenohumeral joint distension for adhesive capsulitis: a randomized trial. Arthritis and Rheumatism 2007;57:1027‐37. - PubMed
Bulgen 1984 {published data only}
    1. Bulgen DY, Binder AI, Hazleman Bl, Dutton J, Roberts S. Frozen shoulder: prospective clinical study with an evaluation of three treatment regimens. Annals of the Rheumatic Diseases 1984;43:353‐60. - PMC - PubMed
Carette 2003 {published data only}
    1. Carette S, Moffet H, Tardif J, Bessette L, Morin F, Frémont P, et al. Intraarticular corticosteroids, supervised physiotherapy, or a combination of the two in the treatment of adhesive capsulitis of the shoulder: a placebo‐controlled trial. Arthritis and Rheumatism 2003;48:829‐38. - PubMed
Celik 2010 {published data only}
    1. Celik D. Comparison of the outcomes of two different exercise programs on frozen shoulder. Acta Orthopaedica et Traumatologica Turcica 2010;44:285‐92. - PubMed
Chan 2010 {published data only}
    1. Chan S, Hill R, Kerr J. Passive joint mobilisation: does it enhance outcome of adhesive capsulitis of the shoulder following corticosteroid injection?. International Musculoskeletal Medicine 2010;32:58‐67.
Chauhan 2011 {published data only}
    1. Chauhan V, Saxena S, Grover S. Effect of deep transverse friction massage and capsular stretching in idiopathic adhesive capsulitis. Indian Journal of Physiotherapy & Occupational Therapy 2011;5:185‐8.
Cheing 2008 {published data only}
    1. Cheing GLY, So EML, Chao CYL. Effectiveness of electroacupuncture and interferential electrotherapy in the management of frozen shoulder. Journal of Rehabilitation Medicine 2008;40:166‐70. - PubMed
Dacre 1989 {published data only}
    1. Dacre JE, Beeney N, Scott DL. Injections and physiotherapy for the painful stiff shoulder. Annals of the Rheumatic Diseases 1989;48:322‐5. - PMC - PubMed
Dundar 2009 {published data only}
    1. Dundar U, Toktas H, Cakir T, Evcik D, Kavuncu V. Continuous passive motion provides good pain control in patients with adhesive capsulitis. International Journal of Rehabilitation Research 2009;32:193‐8. - PubMed
Ghosh 2012 {published data only}
    1. Ghosh TK, Bera AK, Hossain ME, Sarkar PS. Comparison of results of three different methods of treatment for adhesive capsulitis of shoulder. Journal of the Indian Medical Association 2012;110(11):827‐8. - PubMed
Guler‐Uysal 2004 {published data only}
    1. Guler‐Uysal F, Kozanoglu E. Comparison of the early response to two methods of rehabilitation in adhesive capsulitis. Swiss Medical Weekly 2004;134:353‐8. - PubMed
Harsimran 2011 {published data only}
    1. Harsimran K, Ranganath G, Ravi SR. Comparing effectiveness of antero‐posterior and postero‐anterior glides on shoulder range of motion in adhesive capsulitis—a pilot study. Indian Journal of Physiotherapy & Occupational Therapy 2011;5:69‐72.
Johnson 2007 {published data only}
    1. Johnson AJ, Godges JJ, Zimmerman GJ, Ounanian LL. The effect of anterior versus posterior glide joint mobilization on external rotation range of motion in patients with shoulder adhesive capsulitis. Journal of Orthopaedic and Sports Physical Therapy 2007;37:88‐99. - PubMed
Ma 2006 {published data only}
    1. Ma T, Kao MJ, Lin IH, Chiu YL, Chien C, Ho TJ, et al. A study on the clinical effects of physical therapy and acupuncture to treat spontaneous frozen shoulder. The American Journal of Chinese Medicine 2006;34:759‐75. - PubMed
Maricar 1999 {published data only}
    1. Maricar NN, Chok B. A comparison of the effect of manual therapy with exercise therapy and exercise therapy alone for stiff shoulders. Physiotherapy Singapore 1999;2(3):99‐104.
Maryam 2012 {published data only}
    1. Maryam M, Zahra K, Adeleh B, Morteza Y. Comparison of corticosteroid injections, physiotherapy, and combination therapy in treatment of frozen shoulder. Pakistan Journal of Medical Sciences 2012;28:648‐51.
Nellutla 2009 {published data only}
    1. Nellutla M, Gin P. Comparative study between efficacy of PNF movement patterns versus conventional free exercises on functional activities among patients with chronic peri‐arthritis of shoulder. Indian Journal of Physiotherapy & Occupational Therapy 2011;5:62‐7.
    1. Nellutla M, Giri P, M'Kumbuzi VRP, Patel HC. PNF movement patterns compared to the use of conventional free exercises to improve joint ROM in chronic peri‐arthritis of the shoulder. Indian Journal of Physiotherapy & Occupational Therapy 2009;3:31‐4.
Nicholson 1985 {published data only}
    1. Nicholson GG. The effects of passive joint mobilization on pain and hypomobility associated with adhesive capsulitis of the shoulder. Journal of Orthopaedic and Sports Physical Therapy 1985;6:238‐46. - PubMed
Pajareya 2004 {published data only}
    1. Pajareya K, Chadchavalpanichaya N, Painmanakit S, Kaidwan C, Puttaruksa P, Wongsaranuchit Y. Effectiveness of physical therapy for patients with adhesive capsulitis: a randomized controlled trial. Journal of the Medical Association of Thailand 2004;87:473‐80. - PubMed
Rainbow 2008 {published data only}
    1. Rainbow DM, Weston JP, Brantingham JW, Globe G, Lee F. A prospective clinical trial comparing chiropractic manipulation and exercise therapy vs. chiropractic mobilization and exercise therapy for treatment of patients suffering from adhesive capsulitis/frozen shoulder. Journal of the American Chiropractic Association 2008;45:12‐28.
Ryans 2005 {published data only}
    1. Ryans I, Montgomery A, Galway R, Kernohan WG, McKane R. A randomized controlled trial of intra‐articular triamcinolone and/or physiotherapy in shoulder capsulitis. Rheumatology 2005;44:529‐35. - PubMed
Samnani 2004 {published data only}
    1. Samnani M. Passive exercises coupled with therapeutic activities—a comparative study in the management of frozen shoulder. Indian Journal of Occupational Therapy 2004;36:37‐40.
Sharad 2011 {published data only}
    1. Sharad KS. A Comparative study on the efficacy of end range mobilization techniques in treatment of adhesive capsulitis of shoulder. Indian Journal of Physiotherapy & Occupational Therapy 2011;5:28‐31.
Shrivastava 2011 {published data only}
    1. Shrivastava A, Shyam AK, Sabnis S, Sancheti P. Randomised controlled study of Mulligan's vs. Maitland's mobilization technique in adhesive capsulitis of shoulder joint. Indian Journal of Physiotherapy & Occupational Therapy 2011;5:12‐5.
Sirajuddin 2010 {published data only}
    1. Sirajuddin M, Quddus N, Grover D. Comparison of anterior versus posterior glide mobilisation techniques for improving internal rotation range of motion in shoulder adhesive capsulitis. Indian Journal of Physiotherapy & Occupational Therapy 2010;4:152‐7.
Tanaka 2010 {published data only}
    1. Tanaka K, Saura R, Takahashi N, Hiura Y, Hashimoto R. Joint mobilization versus self‐exercises for limited glenohumeral joint mobility: randomized controlled study of management of rehabilitation. Clinical Rheumatology 2010;29:1439‐44. - PubMed
van der Windt 1998 {published data only}
    1. Windt D, Koes BW, Deville W, Boeke AJP, Jong BA, Bouter LM. Effectiveness of corticosteroid injections versus physiotherapy for treatment of painful stiff shoulder in primary care: randomised trial. British Medical Journal 1998;317:1292‐6. - PMC - PubMed
Vermeulen 2006 {published data only}
    1. Vermeulen HM, Rozing PM, Obermann WR, Cessie S, Vliet Vlieland TP. Comparison of high‐grade and low‐grade mobilization techniques in the management of adhesive capsulitis of the shoulder: randomized controlled trial. Physical Therapy 2006;86:355‐68. - PubMed
    1. Hout WB, Vermeulen HM, Rozing PM, Vliet Vlieland TP. Impact of adhesive capsulitis and economic evaluation of high‐grade and low‐grade mobilisation techniques. Australian Journal of Physiotherapy 2005;51:141‐9. - PubMed
Wen 2009 {published data only}
    1. Wen L. Analysis on effect of functional exercises to promote rehabilitation of patients with periarthritis of shoulder. Chinese Nursing Research 2009;23:1925‐6.
Yan 2005 {published data only}
    1. Yan F. Comparison of dumbbell gymnastics and bare‐handed exercise in ameliorating the symptoms of shoulder periarthritis. Chinese Journal of Clinical Rehabilitation 2005;7:187‐9.
Yang 2007 {published data only}
    1. Yang JL, Chang CW, Chen SY, Wang SF, Lin JJ. Mobilization techniques in subjects with frozen shoulder syndrome: randomized multiple‐treatment trial. Physical Therapy 2007;87:1307‐15. - PubMed
Yang 2012 {published data only}
    1. Yang JL, Jan MH, Chang CW, Lin JJ. Effectiveness of the end‐range mobilization and scapular mobilization approach in a subgroup of subjects with frozen shoulder syndrome: a randomized control trial. Manual Therapy 2012;17:47‐52. - PubMed

References to studies excluded from this review

Abdelshafi 2011 {published data only}
    1. Abdelshafi ME, Yosry M, Elmulla AF, Al‐Shahawy EA, Adou Aly M, Eliewa EA. Relief of chronic shoulder pain: a comparative study of three approaches. Middle East Journal of Anesthesiology 2011;21:83‐92. - PubMed
Alicicco 2000 {published data only}
    1. Alicicco E, Chinni LM, Castellano V, Aparo UL. Hyperthermia in scapulohumeral periarthritis due to overuse in athletes. Journal of Sports Sciences 2000;18:489.
Amir‐us‐Saqlain 2007 {published data only}
    1. Amir‐us‐Saqlain H, Zubairi A, Taufiq I. Functional outcome of frozen shoulder after manipulation under anaesthesia. Journal of Pakistan Medical Association 2007;57:181‐5. - PubMed
Arslan 2001 {published data only}
    1. Arslan S, Celiker R. Comparison of the efficacy of local corticosteroid injections and physiotherapy for the treatment of adhesive capsulitis. Rheumatology International 2001;21:20‐3. - PubMed
Bumin 2001 {published data only}
    1. Bumin G, Can F. Effects of iontophoresis and phonophoresis methods on pain in cases with shoulder periarthritis. Pain Clinic 2001;13:159‐62.
Calis 2006 {published data only}
    1. Calis M, Demir H, Ulker S, Kirnap M, Duygulu F, Calis HT. Is intraarticular sodium hyaluronate injection an alternative treatment in patients with adhesive capsulitis?. Rheumatology International 2006;26:536‐40. - PubMed
Diercks 2004 {published data only}
    1. Diercks RL, Stevens M. Gentle thawing of the frozen shoulder: a prospective study of supervised neglect versus intensive physical therapy in seventy‐seven patients with frozen shoulder syndrome followed up for two years. Journal of Shoulder and Elbow Surgery 2004;13:499‐502. - PubMed
Khan 2005 {published data only}
    1. Khan AA, Mowla A, Shakoor MA, Rahman MR. Arthrographic distension of the shoulder joint in the management of frozen shoulder. Mymensingh Medical Journal 2005;14:67‐70. - PubMed
Kivimaki 2007 {published data only}
    1. Kivimaki J, Pohjolainen T, Malmivaara A, Kannisto M, Guillaume J, Seitsalo S, et al. Manipulation under anesthesia with home exercises versus home exercises alone in the treatment of frozen shoulder: a randomized, controlled trial with 125 patients. Journal of Shoulder and Elbow Surgery 2007;16:722‐6. - PubMed
Koh 2013 {published data only}
    1. Koh PS, Seo BK, Cho NS, Park HS, Park DS, Baek YH. Clinical effectiveness of bee venom acupuncture and physiotherapy in the treatment of adhesive capsulitis: a randomized controlled trial. Journal of Shoulder and Elbow Surgery 2013;22(8):1053‐62. - PubMed
Leclaire 1991 {published data only}
    1. Leclaire R, Bourgouin J. Electromagnetic treatment of shoulder periarthritis: a randomized controlled trial of the efficiency and tolerance of magnetotherapy. Archives of Physical Medicine and Rehabilitation 1991;72:284‐7. - PubMed
Lee 1973 {published data only}
    1. Lee M, Haq AM, Wright V, Longton EB. Periarthritis of the shoulder: a controlled trial of physiotherapy. Physiotherapy 1973;59:312‐5. - PubMed
Leung 2008 {published data only}
    1. Leung MS, Cheing GL. Effects of deep and superficial heating in the management of frozen shoulder. Journal of Rehabilitation Medicine 2008;40:145‐50. - PubMed
Longbottom 2009 {published data only}
    1. Longbottom J, Green A. Effectiveness of single‐point acupuncture to Stomach 38 (Tiaokou) on pain and disability in subjects with frozen shoulder. Journal of the Acupuncture Association of Chartered Physiotherapists 2009:37‐46.
Ma 2013 {published data only}
    1. Ma S‐Y, Je HD, Jeong JH, Kim H‐Y, Kim H‐D. Effects of whole‐body cryotherapy in the management of adhesive capsulitis of the shoulder. Archives of Physical Medicine and Rehabilitation 2013;94(1):9‐16. - PubMed
Rizk 1991 {published data only}
    1. Rizk TE, Pinals RS, Talaiver AS. Corticosteroid injections in adhesive capsulitis: investigation of their value and site. Archives of Physical Medicine and Rehabilitation 1991;72:20‐2. - PubMed
Srour 2008 {published data only}
    1. Srour F. Use of cold for the management of acute retractile capsulitis of the shoulder joint. Kinesitherapie Revue 2008, (83):29‐33.
Zhu 2004 {published data only}
    1. Zhu ZZ, Liu CM, Feng WX. Analgesic effects of traditional Chinese medicine iontophoresis and rehabilitation training on periarthritis of shoulder: a randomized controlled study. Chinese Journal of Clinical Rehabilitation 2004;8:2698‐9.

References to studies awaiting assessment

Doner 2013 {published data only}
    1. Doner G, Guven Z, Atalay A, Celiker R. Evalution of Mulligan's technique for adhesive capsulitis of the shoulder. Journal of Rehabilitation Medicine 2013;45(1):87‐91. - PubMed
Fink 2012 {published data only}
    1. Fink M, Schiller J, Buhck H. Efficacy of a manual treatment method according to the fascial distortion model in the management of contracted ("frozen") shoulder. Zeitschrift für Orthopädie und Unfallchirurgie 2012;150(4):420‐7. - PubMed
Ibrahim 2013 {published data only}
    1. Ibrahim M, Donatelli R, Hellman M, Echternach J. Efficacy of a static progressive stretch device as an adjunct to physical therapy in treating adhesive capsulitis of the shoulder: a prospective, randomised study. Physiotherapy 2013:pii:S0031‐9406(13)00085‐0. doi: 10.1016/j.physio.2013.08.006. [Epub ahead of print]. - PubMed
Russell 2014 {published data only}
    1. Russell S, Jariwala A, Conlon R, Selfe J, Richards J, Walton M. A blinded, randomized, controlled trial assessing conservative management strategies for frozen shoulder. Journal of Shoulder and Elbow Surgery 2014;23(4):500‐7. - PubMed
Uddin 2012 {published data only}
    1. Uddin T, Raihan H, Bashar MS, Rahman S. Effectiveness of supervised physiotherapy on patients with adhesive capsulitis. Journal of Rehabilitation Medicine 2012;44(Suppl 52):65‐66.
Wies 2003 {published data only}
    1. Wies J. A pilot randomised placebo controlled trial of osteopathic and physiotherapy treatment for frozen shoulder. Journal of Osteopathic Medicine 2003;6:40.

References to ongoing studies

NCT00873158 {published data only}
    1. http://clinicaltrials.gov/show/NCT00873158. Outcomes following dynamic splinting and/or physical therapy for patients with adhesive capsulitis.
NCT01249040 {published data only}
    1. http://clinicaltrials.gov/show/NCT01249040. The study of different treatment programs for patients with frozen shoulder.
NCT01483963 {published data only}
    1. http://clinicaltrials.gov/show/NCT01483963. A Phase 2a, open‐label, dose‐ranging study of the safety and effectiveness of AA4500 for the treatment of adhesive capsulitis of the shoulder.

Additional references

Ballantyne 1993
    1. Ballantyne BT, O'Hare SJ, Paschall JL, Pavia‐Smith MM, Pitz AM, Gillon JF, et al. Electromyographic activity of selected shoulder muscles in commonly used therapeutic exercises. Physical Therapy 1993;73:668‐77. - PubMed
Binder 1984
    1. Binder AI, Bulgen DY, Hazelman BL, Roberts S. Frozen shoulder: a long‐term prospective study. Annals of the Rheumatic Diseases 1984;43:361‐4. - PMC - PubMed
Blanchard 2010
    1. Blanchard V, Barr S, Cerisola FL. The effectiveness of corticosteroid injections compared with physiotherapeutic interventions for adhesive capsulitis: a systematic review. Physiotherapy 2010;96:95‐107. - PubMed
Cates 2004 [Computer program]
    1. Dr Chris Cates EBM website. http://www.nntonline.net/. Visual Rx NNT Calculator. Dr Chris Cates EBM website. http://www.nntonline.net/, 2004.
Codman 1934
    1. Codman EA. The Shoulder. Boston: Thomas Toddog, 1934.
Deeks 2011
    1. Deeks JJ, Higgins JPT, Altman DG. Chapter 9: Analysing data and undertaking meta‐analyses. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011:www.cochrane‐handbook.org.
Dwan 2011
    1. Dwan K, Altman DG, Cresswell L, Blundell M, Gamble CL, Williamson PR. Comparison of protocols and registry entries to published reports for randomised controlled trials. Cochrane Database of Systematic Reviews 2011, Issue 1. [DOI: 10.1002/14651858.MR000031.pub2] - DOI - PMC - PubMed
Dworkin 2008
    1. Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. The Journal of Pain 2008;9(2):105‐21. - PubMed
Ebrahim 2013
    1. Ebrahim S, Akl EA, Mustafa RA, Sun X, Walter SD, Heels‐Ansdell D, et al. Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers. Journal of Clinical Epidemiology 2013;66(9):1014‐21. - PubMed
Favejee 2011
    1. Favejee MM, Huisstede BMA, Koes BW. Frozen shoulder: the effectiveness of conservative and surgical interventions—systematic review. British Journal of Sports Medicine 2011;45:49‐56. - PubMed
Frank 1984
    1. Frank C, Akeson WH, Woo SL, Amiel D, Couts RD. Physiology and therapeutic value of passive joint motion. Clinical Orthopaedics and Related Research 1984;185:113‐25. - PubMed
Hanchard 2011a
    1. Hanchard NCA, Goodchild L, Thompson J, O'Brien T, Davison D, Richardson C. A questionnaire survey of UK physiotherapists on the diagnosis and management of contracted (frozen) shoulder. Physiotherapy 2011;97:115‐25. - PubMed
Hanchard 2011b
    1. Hanchard N, Goodchild L, Thompson J, O’Brien T, Richardson C, Davison D, et al. Evidence‐based clinical guidelines for the diagnosis, assessment and physiotherapy management of contracted (frozen) shoulder, v. 1.7, ‘standard’ physiotherapy. Endorsed by the Chartered Society of Physiotherapy, www.csp.org.uk/skipp, 2011. - PubMed
Hand 2008
    1. Hand C, Clipsham K, Rees JL, Carr AJ. Long‐term outcome of frozen shoulder. Journal of Shoulder and Elbow Surgery 2008;17:231‐6. - PubMed
Hazelman 1972
    1. Hazleman BL. The painful stiff shoulder. Rheumatology and Physical Medicine 1972;11(8):413‐21. - PubMed
Higgins 2002
    1. Higgins JPT, Thompson SG. Quantifying heterogeneity in meta‐analysis. Statistics in Medicine 2002;21(11):1539‐58. [PUBMED: 12111919] - PubMed
Higgins 2011a
    1. Higgins JPT, Altman DG, Sterne JAC. Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, www.cochrane‐handbook.org.
Kaltenborn 1976
    1. Kaltenborn FM. Manual Therapy for the Extremity Joints. Oslo, Norway: Olaf Norlis Bokhandel, 1976.
Kirkham 2010
    1. Kirkham JJ, Dwan KM, Altman DG, Gamble C, Dodd S, Smyth R, et al. The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ 2010;340:c365. - PubMed
Maitland 1977
    1. Maitland GD. Peripheral manipulation. London, United Kingdom: Butterworths, 1977.
Mangus 2002
    1. Mangus BC, Hoffman LA, Hoffman MA, Altenburger P. Basic principles of extremity joint mobilization using a Kaltenborn approach. Journal of Sport Rehabilitation 2002;11:235‐50.
Mao 1997
    1. Mao CY, Jaw WC, Cheng HC. Frozen shoulder: correlation between the response to physical therapy and follow‐up shoulder arthrography. Archives of Physical Medicine and Rehabilitation 1997;78:857‐9. - PubMed
Maund 2012
    1. Maund E, Craig D, Suekarran S, Neilson Ar, Wright K, Brealey S, et al. Management of frozen shoulder: a systematic review and cost‐effectiveness analysis. Health Technology Assessment 2012;16:1‐264. - PMC - PubMed
Moore 2010
    1. Moore RA, Eccleston C, Derry S, Wiffen P, Bell RF, Straube S, et al. "Evidence" in chronic pain—establishing best practice in the reporting of systematic reviews. Pain 2010;150(3):386‐9. - PubMed
Neviaser 1945
    1. Neviaser JS. Adhesive capsulitis of the shoulder: a study of the pathological findings in periarthritis of the shoulder. Journal of Bone and Joint Surgery 1945;27:211‐22.
Norris 2012
    1. Norris SL, Holmer HK, Ogden LA, Fu R, Abou‐Setta AM, Viswanathan MS, et al. Selective outcome reporting as a source of bias in reviews of comparative effectiveness. (Prepared by the Oregon Evidence‐based Practice Center under Contract No. 290‐2007‐10057‐I.) AHRQ Publication No. 12‐EHC110‐EF. Rockville, MD: Agency for Healthcare Research and Quality, August 2012. www.effectivehealthcare.ahrq.gov/reports/final.cfm. - PubMed
Page 2013
    1. Page MJ, McKenzie JE, Forbes A. Many scenarios exist for selective inclusion and reporting of results in randomized trials and systematic reviews. Journal of Clinical Epidemiology 2013;66(5):524‐37. - PubMed
Reeves 1975
    1. Reeves B. The natural history of the frozen shoulder syndrome. Scandinavian Journal of Rheumatology 1975;4:193‐6. - PubMed
Savovic 2012
    1. Savović J, Jones HE, Altman DG, Harris RJ, Jüni P, Pildal J, et al. Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials. Annals of Internal Medicine 2012;157(6):429‐38. - PubMed
Schellingerhout 2008
    1. Schellingerhout JM, Verhagen AP, Thomas S, Koes BW. Lack of uniformity in diagnostic labeling of shoulder pain: time for a different approach. Manual Therapy 2008;13:478‐83. - PubMed
Schünemann 2011a
    1. Schünemann HJ, Oxman AD, Higgins JPT, Vist GE, Glasziou P, Guyatt GH. Chapter 11: Presenting results and 'Summary of findings' tables. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011:www.cochrane‐handbook.org.
Schünemann 2011b
    1. Schünemann HJ, Oxman AD, Vist GE, Higgins JPT, Deeks JJ, Glasziou P, Guyatt GH. Chapter 12: Interpreting results and drawing conclusions. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011:www.cochrane‐handbook.org.
Sterne 2011
    1. Sterne JAC, Egger M, Moher D. Chapter 10: Addressing reporting biases. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011:www.cochrane‐handbook.org.
Tekavec 2012
    1. Tekavec E, Joud A, Rittner R, Mikoczy Z, Nordander C, Petersson IF, et al. Population‐based consultation patterns in patients with shoulder pain diagnoses. BMC Musculoskeletal Disorders 2012;13:238. - PMC - PubMed
van der Windt 1995
    1. Windt DA, Koes BW, Jong BA, Bouter LM. Shoulder disorders in general practice: incidence, patient characteristics, and management. Annals of Rheumatic Disease 1995;54:959‐64. - PMC - PubMed
van der Windt 1998b
    1. Windt DAWM, Heijden GJMG, Koes BW, Winter AF, Devillé W, Bouter LM. The responsiveness of the shoulder disability questionnaire. Annals of Rheumatic Disease 1998;57:82‐7. - PMC - PubMed
Vermeulen 2000
    1. Vermeulen HM, Obermann WR, Burger BJ, Kok GJ, Rozing PM, Ende CH. End‐range mobilization techniques in adhesive capsulitis of the shoulder joint: a multiple‐subject case report. Physical Therapy 2000;80:1204–13. - PubMed
Walker 2004
    1. Walker‐Bone K, Palmer KT, Reading I, Coggon D, Cooper C. Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis Care & Research 2004;51:642‐51. - PubMed

References to other published versions of this review

Green 1998
    1. Green S, Buchbinder R, Glazier R, Forbes A. Systematic review of randomised controlled trials of interventions for painful shoulder: selection criteria, outcome assessment and efficacy. British Medical Journal 1998;316:354‐60. - PMC - PubMed
Green 2003
    1. Green S, Buchbinder R, Hetrick S. Physiotherapy interventions for shoulder pain. Cochrane Database of Systematic Reviews 2003, Issue 2. [DOI: 10.1002/14651858.CD004258] - DOI - PMC - PubMed

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