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Case Reports
. 2014 Jun 26;370(26):2499-505.
doi: 10.1056/NEJMoa1401505. Epub 2014 Jun 4.

Evidence for camel-to-human transmission of MERS coronavirus

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Case Reports

Evidence for camel-to-human transmission of MERS coronavirus

Esam I Azhar et al. N Engl J Med. .
Free article

Abstract

We describe the isolation and sequencing of Middle East respiratory syndrome coronavirus (MERS-CoV) obtained from a dromedary camel and from a patient who died of laboratory-confirmed MERS-CoV infection after close contact with camels that had rhinorrhea. Nasal swabs collected from the patient and from one of his nine camels were positive for MERS-CoV RNA. In addition, MERS-CoV was isolated from the patient and the camel. The full genome sequences of the two isolates were identical. Serologic data indicated that MERS-CoV was circulating in the camels but not in the patient before the human infection occurred. These data suggest that this fatal case of human MERS-CoV infection was transmitted through close contact with an infected camel.

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