Plant vacuolar trafficking occurs through distinctly regulated pathways

doi:10.1016/j.cub.2014.05.004

. 2014 Jun 16;24(12):1375-1382.

doi: 10.1016/j.cub.2014.05.004. Epub 2014 May 29.

Plant vacuolar trafficking occurs through distinctly regulated pathways

Kazuo Ebine¹, Takeshi Inoue¹, Jun Ito², Emi Ito¹, Tomohiro Uemura¹, Tatsuaki Goh³, Hiroshi Abe⁴, Ken Sato⁵, Akihiko Nakano⁶, Takashi Ueda⁷

Affiliations

¹ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
² Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0101, Japan.
³ Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.
⁴ Antibiotics Laboratory, RIKEN, and RIKEN Center for Sustainable Resource Science (CSRS), Gene Discovery Research Group, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
⁵ Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8902, Japan.
⁶ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; RIKEN Center for Advanced Photonics, Live Cell Molecular Imaging Research Team, Extreme Photonics Research Group, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
⁷ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Japan Science and Technology Agency (JST), PRESTO, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan. Electronic address: tueda@bs.s.u-tokyo.ac.jp.

PMID: 24881878
DOI: 10.1016/j.cub.2014.05.004

Free article

Plant vacuolar trafficking occurs through distinctly regulated pathways

Kazuo Ebine et al. Curr Biol. 2014.

Free article

. 2014 Jun 16;24(12):1375-1382.

doi: 10.1016/j.cub.2014.05.004. Epub 2014 May 29.

Authors

Kazuo Ebine¹, Takeshi Inoue¹, Jun Ito², Emi Ito¹, Tomohiro Uemura¹, Tatsuaki Goh³, Hiroshi Abe⁴, Ken Sato⁵, Akihiko Nakano⁶, Takashi Ueda⁷

Affiliations

¹ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
² Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Nara 630-0101, Japan.
³ Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.
⁴ Antibiotics Laboratory, RIKEN, and RIKEN Center for Sustainable Resource Science (CSRS), Gene Discovery Research Group, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
⁵ Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8902, Japan.
⁶ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; RIKEN Center for Advanced Photonics, Live Cell Molecular Imaging Research Team, Extreme Photonics Research Group, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
⁷ Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan; Japan Science and Technology Agency (JST), PRESTO, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan. Electronic address: tueda@bs.s.u-tokyo.ac.jp.

PMID: 24881878
DOI: 10.1016/j.cub.2014.05.004

Abstract

The multifunctional vacuole is the largest organelle in plant cells, and many proteins are transported to and stored in this organelle; thus, the vacuole has great physiological and agronomical importance. However, the molecular mechanism and regulation of plant vacuolar traffic remain largely unknown. In this study, we demonstrate that multiple vacuolar trafficking pathways operate in plants. RAB5 and RAB7 are evolutionarily conserved subfamilies of Rab GTPase, whose animal and yeast counterparts regulate vacuolar/endosomal trafficking in a sequential manner. Functional analyses of a putative activating complex for RAB7 indicated that this complex is responsible for maturation from RAB5- to RAB7-positive endosomes in plant cells. Moreover, these machinery components are recruited to a more complex trafficking network. Mutations in RAB5 and RAB7 conferred counteracting effects on the vti11 mutant. Furthermore, impairment of RAB5- and RAB7-dependent pathways differentially affected the transport of distinctive cargos. These results indicate that plants have developed a complex vacuolar transport system distinct from that of nonplant systems by assigning evolutionarily conserved machinery to unique trafficking pathways. These pathways provide a fundamental basis for plant development at the cellular and higher-ordered levels.

PubMed Disclaimer

Cited by

The Rab7 subfamily across Paramecium aurelia species; evidence of high conservation in sequence and function.
Bright LJ, Lynch M. Bright LJ, et al. Small GTPases. 2020 Nov;11(6):421-429. doi: 10.1080/21541248.2018.1502056. Epub 2018 Aug 29. Small GTPases. 2020. PMID: 30156960 Free PMC article.
The retromer CSC subcomplex is recruited by MoYpt7 and sequentially sorted by MoVps17 for effective conidiation and pathogenicity of the rice blast fungus.
Wu C, Lin Y, Zheng H, Abubakar YS, Peng M, Li J, Yu Z, Wang Z, Naqvi NI, Li G, Zhou J, Zheng W. Wu C, et al. Mol Plant Pathol. 2021 Feb;22(2):284-298. doi: 10.1111/mpp.13029. Epub 2020 Dec 21. Mol Plant Pathol. 2021. PMID: 33350057 Free PMC article.
Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole.
Rodriguez-Furlan C, Domozych D, Qian W, Enquist PA, Li X, Zhang C, Schenk R, Winbigler HS, Jackson W, Raikhel NV, Hicks GR. Rodriguez-Furlan C, et al. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21291-21301. doi: 10.1073/pnas.1905321116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570580 Free PMC article.
Update on adaptor protein-3 in Arabidopsis.
Feng QN, Li S, Zhang Y. Feng QN, et al. Plant Signal Behav. 2017 Aug 3;12(8):e1356969. doi: 10.1080/15592324.2017.1356969. Epub 2017 Aug 8. Plant Signal Behav. 2017. PMID: 28786748 Free PMC article. Review.
ENDOSOMAL RAB EFFECTOR WITH PX-DOMAIN, an Interacting Partner of RAB5 GTPases, Regulates Membrane Trafficking to Protein Storage Vacuoles in Arabidopsis.
Sakurai HT, Inoue T, Nakano A, Ueda T. Sakurai HT, et al. Plant Cell. 2016 Jun;28(6):1490-503. doi: 10.1105/tpc.16.00326. Epub 2016 Jun 10. Plant Cell. 2016. PMID: 27288222 Free PMC article.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science
Other Literature Sources
- scite Smart Citations
Molecular Biology Databases
- The Arabidopsis Information Resource

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Plant vacuolar trafficking occurs through distinctly regulated pathways

Affiliations

Plant vacuolar trafficking occurs through distinctly regulated pathways

Authors

Affiliations

Abstract

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Molecular Biology Databases