Case Reports
Detection of retrovirus particles and reverse transcriptase activity in mid-term cultured peripheral blood and lymph node cells from a French woman with Sezary syndrome
Affiliations
- PMID: 2479905
Item in Clipboard
Case Reports
Detection of retrovirus particles and reverse transcriptase activity in mid-term cultured peripheral blood and lymph node cells from a French woman with Sezary syndrome
Nouv Rev Fr Hematol (1978).
1989.
Abstract
Retrovirus particles, with an ultrastructure of type C-virus similar to HTLV-I were observed in several mid-term cultures of leukemic cells derived from a woman with a well characterised Sezary syndrome who had always resided in France. Reverse transcriptase activity was detected in supernatant fluids from day 6 to day 40 of culture. However, negative anti HTLV-I serology and the absence of specific molecular hybridization between leukemic cell DNA and two HTLV-I derived probes, argue against a HTLV-I virus.
Similar articles
-
[Particles with retrovirus appearance and reverse transcriptase activity in cell cultures derived from lymph node biopsies in Hodgkin's disease].C R Acad Sci III. 1987;305(8):295-300. C R Acad Sci III. 1987. PMID: 2443226 French.
-
HTLV-1-like particles and HTLV-1-related DNA sequences in an unambiguous case of Sèzary syndrome.Leukemia. 1994 Jan;8(1):201-7. Leukemia. 1994. PMID: 8289490
-
No evidence for HTLV-I infection in 24 cases of French and Portuguese mycosis fungoïdes and Sezary syndrome (as seen in France).Leukemia. 1991 May;5(5):416-9. Leukemia. 1991. PMID: 2033961
-
Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor.J Clin Invest. 1984 Jun;73(6):1711-8. doi: 10.1172/JCI111379. J Clin Invest. 1984. PMID: 6327770 Free PMC article.
-
Failure to confirm the presence of a retrovirus in cultured lymphocytes from patients with Kawasaki syndrome.Pediatr Res. 1991 May;29(5):417-9. doi: 10.1203/00006450-199105010-00001. Pediatr Res. 1991. PMID: 1716754
Cited by
-
Detection of human T-lymphotropic virus-like particles in cultures of peripheral blood lymphocytes from patients with mycosis fungoides.Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7630-4. doi: 10.1073/pnas.88.17.7630. Proc Natl Acad Sci U S A. 1991. PMID: 1881904 Free PMC article.
-
The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease. A study of 50 patients.J Clin Invest. 1995 Feb;95(2):547-54. doi: 10.1172/JCI117697. J Clin Invest. 1995. PMID: 7860737 Free PMC article. Clinical Trial.