Comment
doi: 10.1016/j.molcel.2014.02.023.
Chaperoned by prebiotic inorganic polyphosphate molecules: an ancient transcription-independent mechanism to restore protein homeostasis
Affiliations
- PMID: 24606917
- DOI: 10.1016/j.molcel.2014.02.023
Item in Clipboard
Comment
Chaperoned by prebiotic inorganic polyphosphate molecules: an ancient transcription-independent mechanism to restore protein homeostasis
Mol Cell.
.
Free article
Abstract
In this issue, Gray et al. (2014) elegantly demonstrate how cells utilize an oxidation-regulated pathway that depletes cellular ATP, lowers proteostatic burden, and leads to accumulation of prebiotic, inorganic polyphosphates with chaperone-like activity for stress protection.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
-
Polyphosphate is a primordial chaperone.Mol Cell. 2014 Mar 6;53(5):689-99. doi: 10.1016/j.molcel.2014.01.012. Epub 2014 Feb 20. Mol Cell. 2014. PMID: 24560923 Free PMC article.
Similar articles
-
Polyphosphate is a primordial chaperone.Mol Cell. 2014 Mar 6;53(5):689-99. doi: 10.1016/j.molcel.2014.01.012. Epub 2014 Feb 20. Mol Cell. 2014. PMID: 24560923 Free PMC article.
-
Oxidative stress protection by polyphosphate--new roles for an old player.Curr Opin Microbiol. 2015 Apr;24:1-6. doi: 10.1016/j.mib.2014.12.004. Epub 2015 Jan 10. Curr Opin Microbiol. 2015. PMID: 25589044 Free PMC article. Review.
-
Stable polyphosphate accumulation by a pseudo-revertant of an Escherichia coli phoU mutant.Biotechnol Lett. 2013 May;35(5):695-701. doi: 10.1007/s10529-012-1133-y. Epub 2013 Jan 4. Biotechnol Lett. 2013. PMID: 23288295
-
A Stringent Analysis of Polyphosphate Dynamics in Escherichia coli.J Bacteriol. 2019 Apr 9;201(9):e00070-19. doi: 10.1128/JB.00070-19. Print 2019 May 1. J Bacteriol. 2019. PMID: 30782636 Free PMC article.
-
Chaperoned protein disaggregation--the ClpB ring uses its central channel.Cell. 2004 Nov 24;119(5):579-81. doi: 10.1016/j.cell.2004.11.018. Cell. 2004. PMID: 15550237 Review.
Cited by
-
What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?Front Microbiol. 2016 Nov 23;7:1882. doi: 10.3389/fmicb.2016.01882. eCollection 2016. Front Microbiol. 2016. PMID: 27933045 Free PMC article.
-
Dynamic Polyphosphate Metabolism Coordinating with Manganese Ions Defends against Oxidative Stress in the Extreme Bacterium Deinococcus radiodurans.Appl Environ Microbiol. 2021 Mar 11;87(7):e02785-20. doi: 10.1128/AEM.02785-20. Print 2021 Mar 11. Appl Environ Microbiol. 2021. PMID: 33452031 Free PMC article.
-
Inorganic polyphosphate interacts with nucleolar and glycosomal proteins in trypanosomatids.Mol Microbiol. 2018 Dec;110(6):973-994. doi: 10.1111/mmi.14131. Epub 2018 Oct 18. Mol Microbiol. 2018. PMID: 30230089 Free PMC article.
-
Bacterial Defense Systems against the Neutrophilic Oxidant Hypochlorous Acid.Infect Immun. 2020 Jun 22;88(7):e00964-19. doi: 10.1128/IAI.00964-19. Print 2020 Jun 22. Infect Immun. 2020. PMID: 32152198 Free PMC article. Review.
-
Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation.Arch Biochem Biophys. 2019 Feb 15;662:177-189. doi: 10.1016/j.abb.2018.12.019. Epub 2018 Dec 17. Arch Biochem Biophys. 2019. PMID: 30571965 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
