Membrane composition and dynamics: a target of bioactive virgin olive oil constituents
- PMID: 24440426
- DOI: 10.1016/j.bbamem.2014.01.007
Membrane composition and dynamics: a target of bioactive virgin olive oil constituents
Abstract
The endogenous synthesis of lipids, which requires suitable dietary raw materials, is critical for the formation of membrane bilayers. In eukaryotic cells, phospholipids are the predominant membrane lipids and consist of hydrophobic acyl chains attached to a hydrophilic head group. The relative balance between saturated, monounsaturated, and polyunsaturated acyl chains is required for the organization and normal function of membranes. Virgin olive oil is the richest natural dietary source of the monounsaturated lipid oleic acid and is one of the key components of the healthy Mediterranean diet. Virgin olive oil also contains a unique constellation of many other lipophilic and amphipathic constituents whose health benefits are still being discovered. The focus of this review is the latest evidence regarding the impact of oleic acid and the minor constituents of virgin olive oil on the arrangement and behavior of lipid bilayers. We highlight the relevance of these interactions to the potential use of virgin olive oil in preserving the functional properties of membranes to maintain health and in modulating membrane functions that can be altered in several pathologies. This article is part of a Special Issue entitled: Membrane Structure and Function: Relevance in the Cell's Physiology, Pathology and Therapy.
Keywords: Health/disease; Membrane; Minor constituent; Oleic acid; Phospholipid; Virgin olive oil.
Copyright © 2014 Elsevier B.V. All rights reserved.
Similar articles
-
International conference on the healthy effect of virgin olive oil.Eur J Clin Invest. 2005 Jul;35(7):421-4. doi: 10.1111/j.1365-2362.2005.01516.x. Eur J Clin Invest. 2005. PMID: 16008542 Review.
-
Effects of dietary extra virgin olive oil on serum lipid resistance to oxidation and fatty acid composition in elderly lipidemic patients.Bratisl Lek Listy. 2003;104(7-8):218-21. Bratisl Lek Listy. 2003. PMID: 15168866
-
Dietary fat type (virgin olive vs. sunflower oils) affects age-related changes in DNA double-strand-breaks, antioxidant capacity and blood lipids in rats.Exp Gerontol. 2004 Aug;39(8):1189-98. doi: 10.1016/j.exger.2004.05.002. Exp Gerontol. 2004. PMID: 15288693
-
Changes in the Fatty Acid Profile and Phospholipid Molecular Species Composition of Human Erythrocyte Membranes after Hybrid Palm and Extra Virgin Olive Oil Supplementation.J Agric Food Chem. 2016 Jul 13;64(27):5499-507. doi: 10.1021/acs.jafc.6b01903. Epub 2016 Jun 29. J Agric Food Chem. 2016. PMID: 27315139
-
The role of virgin olive oil components in the modulation of endothelial function.J Nutr Biochem. 2006 Jul;17(7):429-45. doi: 10.1016/j.jnutbio.2005.11.007. Epub 2005 Dec 12. J Nutr Biochem. 2006. PMID: 16481154 Review.
Cited by
-
Neuroprotective effects of oleic acid in rodent models of cerebral ischaemia.Sci Rep. 2019 Jul 24;9(1):10732. doi: 10.1038/s41598-019-47057-z. Sci Rep. 2019. PMID: 31341184 Free PMC article.
-
Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation.Mediators Inflamm. 2015;2015:260465. doi: 10.1155/2015/260465. Epub 2015 Nov 12. Mediators Inflamm. 2015. PMID: 26640323 Free PMC article. Review.
-
Supercritical CO2 Extraction of Phytocompounds from Olive Pomace Subjected to Different Drying Methods.Molecules. 2021 Jan 23;26(3):598. doi: 10.3390/molecules26030598. Molecules. 2021. PMID: 33498727 Free PMC article.
-
Oleic acid-loaded nanostructured lipid carrier inhibit neutrophil activities in the presence of albumin and alleviates skin inflammation.Int J Nanomedicine. 2019 Aug 16;14:6539-6553. doi: 10.2147/IJN.S208489. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31496699 Free PMC article.
-
Effect of high-carbohydrate or high-monounsaturated fatty acid diets on blood pressure: a systematic review and meta-analysis of randomized controlled trials.Nutr Rev. 2019 Jan 1;77(1):19-31. doi: 10.1093/nutrit/nuy040. Nutr Rev. 2019. PMID: 30165599 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources