A long-playing CD about the γδ TCR repertoire

doi:10.1016/j.immuni.2013.11.016

Comment

. 2013 Dec 12;39(6):994-6.

doi: 10.1016/j.immuni.2013.11.016.

A long-playing CD about the γδ TCR repertoire

Adrian Hayday¹, Pierre Vantourout²

Affiliations

¹ Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK; Medical Research Council Centre for Transplantation Biology, London SE1 9RT, UK; Comprehensive Biomedical Research Centre of Guy's and St Thomas' Hospitals and King's College London, London SE1 9RT, UK. Electronic address: adrian.hayday@kcl.ac.uk.
² Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK.

PMID: 24332025
DOI: 10.1016/j.immuni.2013.11.016

Free article

Comment

A long-playing CD about the γδ TCR repertoire

Adrian Hayday et al. Immunity. 2013.

Free article

. 2013 Dec 12;39(6):994-6.

doi: 10.1016/j.immuni.2013.11.016.

Authors

Adrian Hayday¹, Pierre Vantourout²

Affiliations

¹ Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK; Medical Research Council Centre for Transplantation Biology, London SE1 9RT, UK; Comprehensive Biomedical Research Centre of Guy's and St Thomas' Hospitals and King's College London, London SE1 9RT, UK. Electronic address: adrian.hayday@kcl.ac.uk.
² Peter Gorer Department of Immunobiology, King's College London, London SE1 9RT, UK; London Research Institute, Cancer Research UK, London WC2A 3LY, UK.

PMID: 24332025
DOI: 10.1016/j.immuni.2013.11.016

Abstract

In this issue of Immunity, a study by Luoma et al. (2013) provides structural evidence for direct interactions of human Vδ1(+) T cell receptors with CD1d, capping a long trail of evidence that CD1 might be a major influence on γδ T cell biology.

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Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells.
Luoma AM, Castro CD, Mayassi T, Bembinster LA, Bai L, Picard D, Anderson B, Scharf L, Kung JE, Sibener LV, Savage PB, Jabri B, Bendelac A, Adams EJ. Luoma AM, et al. Immunity. 2013 Dec 12;39(6):1032-42. doi: 10.1016/j.immuni.2013.11.001. Epub 2013 Nov 14. Immunity. 2013. PMID: 24239091 Free PMC article.

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A long-playing CD about the γδ TCR repertoire

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A long-playing CD about the γδ TCR repertoire

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