Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Oct;15(4 Pt 1):645-9.
doi: 10.1016/s0190-9622(86)70219-3.

Langerhans cells in molluscum contagiosum, verruca vulgaris, plantar wart, and condyloma acuminatum

J Bhawan, Y Dayal, A K Bhan

Langerhans cells in molluscum contagiosum, verruca vulgaris, plantar wart, and condyloma acuminatum

J Bhawan et al. J Am Acad Dermatol. 1986 Oct.

Abstract

To determine a possible role of Langerhans cells in viral infection of skin, we studied the distribution of Langerhans and indeterminate cells in the lesional skin of mollusca contagiosa, verrucae vulgaris, plantar warts, and condylomata acuminata. A total absence of Langerhans and indeterminate cells was observed in molluscum contagiosum, but their number appeared to be normal or increased in the perilesional normal skin. Few Langerhans and indeterminate cells were seen in the suprabasal location in verrucae vulgaris and plantar warts, and normal numbers were noted in the perilesional skin. In contrast, a larger number of Langerhans and indeterminate cells reaching up to stratum granulosum were found in the condylomata acuminata. It is possible that alteration of keratinocytes by viral infection may effect the migration of Langerhans cells to the epidermis. The lack of Langerhans cells may lead to a paucity of inflammatory response (in particular, T cell-mediated response) to the cells infected with the virus.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources