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Comment
. 2013 Oct;10(10):e1001539.
doi: 10.1371/journal.pmed.1001539. Epub 2013 Oct 22.

A transcriptional signature for active TB: have we found the needle in the haystack?

Adithya Cattamanchi  1 , Nicholas D Walter, John Z Metcalfe, J Lucian Davis
Affiliations
Comment

A transcriptional signature for active TB: have we found the needle in the haystack?

Adithya Cattamanchi et al. PLoS Med. 2013 Oct.

Abstract

Adithya Cattamanchi and colleagues reflect on recent research by Michael Levin and coworkers into the use of whole blood mRNA expression signatures to detect tuberculosis. The authors highlight challenges faced in getting this promising technology into clinics in low-resource settings. Please see later in the article for the Editors' Summary.

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Conflict of interest statement

J. Lucian Davis is involved in additional research concerning blood gene expression profiling and tuberculosis. The other authors have declared that no competing interests exist.

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