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Review
. 2013;56(6):395-412.
doi: 10.1159/000354561. Epub 2013 Oct 17.

Describing the silent human virome with an emphasis on giant viruses

Nikolay Popgeorgiev  1 , Sarah Temmam, Didier Raoult, Christelle Desnues
Affiliations
Free article
Review

Describing the silent human virome with an emphasis on giant viruses

Nikolay Popgeorgiev et al. Intervirology. 2013.
Free article

Abstract

Viruses are the most abundant obligate intracellular entities in our body. Until recently, they were only considered to be pathogens that caused a broad array of pathologies, ranging from mild disease to deaths in the most severe cases. However, recent advances in unbiased mass sequencing techniques as well as increasing epidemiological evidence have indicated that the human body is home to diverse viral species under non-pathological conditions. Despite these studies, the description of the presumably healthy viral flora, i.e. the normal human virome, is still in its infancy regarding viral composition and dynamics. This review summarizes our current knowledge of the human virome under non-pathological conditions.

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